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Christopher J. A. Pugh
Researcher at Cardiff Metropolitan University
Publications - 46
Citations - 1221
Christopher J. A. Pugh is an academic researcher from Cardiff Metropolitan University. The author has contributed to research in topics: Medicine & Cardiorespiratory fitness. The author has an hindex of 17, co-authored 36 publications receiving 946 citations. Previous affiliations of Christopher J. A. Pugh include Liverpool John Moores University & University of Western Australia.
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Journal ArticleDOI
Polycystic Ovary Syndrome with Hyperandrogenism Is Characterized by an Increased Risk of Hepatic Steatosis Compared to Nonhyperandrogenic PCOS Phenotypes and Healthy Controls, Independent of Obesity and Insulin Resistance
Helen Jones,Victoria S. Sprung,Christopher J. A. Pugh,Christina Daousi,Andrew J. Irwin,Nabil Aziz,V.L. Adams,E. Louise Thomas,Jimmy D. Bell,Graham J. Kemp,Daniel J. Cuthbertson +10 more
TL;DR: It is suggested that HA-PCOS is associated with hepatic steatosis, independent of obesity and insulin resistance, in women with polycystic ovary syndrome.
Journal ArticleDOI
Endothelial function measured using flow-mediated dilation in polycystic ovary syndrome: a meta-analysis of the observational studies.
Victoria S. Sprung,Greg Atkinson,Daniel J. Cuthbertson,Christopher J. A. Pugh,Nabil Aziz,Daniel J. Green,Daniel J. Green,N. Timothy Cable,Helen Jones +8 more
TL;DR: A systematic review and meta‐analysis was conducted to examine to what extent FMD is impaired in PCOS and to explore the influence of potential moderators of FMD reduction, such as age and BMI.
Journal ArticleDOI
Exercise training reverses endothelial dysfunction in nonalcoholic fatty liver disease
Christopher J. A. Pugh,Christopher J. A. Pugh,Victoria S. Sprung,Graham J. Kemp,Paul G. Richardson,Fariba Shojaee-Moradie,A. Margot Umpleby,Daniel J. Green,Daniel J. Green,N. Timothy Cable,Helen Jones,Daniel J. Cuthbertson +11 more
TL;DR: Exercise training, but not conventional care, significantly improved V̇o2 peak and cannot be fully explained by excess VAT but can be reversed with exercise training; this has potential implications for the primary prevention of CVD in NAFLD.
Journal ArticleDOI
Dissociation between exercise-induced reduction in liver fat and changes in hepatic and peripheral glucose homoeostasis in obese patients with non-alcoholic fatty liver disease
Daniel J. Cuthbertson,Fariba Shojaee-Moradie,Victoria S. Sprung,Helen Jones,Christopher J. A. Pugh,Paul G. Richardson,Graham J. Kemp,M. Barrett,Nicola Jackson,E L Thomas,Jimmy D. Bell,A. M. Umpleby +11 more
TL;DR: Although supervised exercise effectively reduced liver fat, improving peripheral IR in NAFLD, the reduction in liver fat was insufficient to improve hepatic IR.
Journal ArticleDOI
Exercise training and artery function in humans: nonresponse and its relationship to cardiovascular risk factors
Daniel J. Green,Thijs M. H. Eijsvogels,Yvette M. Bouts,Andrew Maiorana,Louise H. Naylor,Ralph R. Scholten,Marc E. A. Spaanderman,Christopher J. A. Pugh,Victoria S. Sprung,Tim H. A. Schreuder,Helen Jones,Tim Cable,Maria T. E. Hopman,Dick H. J. Thijssen +13 more
TL;DR: It is found that, while some subjects do not demonstrate increases following exercise training, improvement in FMD% is present in those with lower pretraining body weight and endothelial function, indicating that some cardioprotective effects of exercise training are independent of improvement in risk factors.