S
Shu Feng Lei
Researcher at University of Missouri–Kansas City
Publications - 27
Citations - 1622
Shu Feng Lei is an academic researcher from University of Missouri–Kansas City. The author has contributed to research in topics: Single-nucleotide polymorphism & Bone density. The author has an hindex of 24, co-authored 27 publications receiving 1512 citations. Previous affiliations of Shu Feng Lei include Hunan Normal University & Tulane University.
Papers
More filters
Journal ArticleDOI
Genome-wide Copy-Number-Variation Study Identified a Susceptibility Gene, UGT2B17, for Osteoporosis
Tie-Lin Yang,Xiang Ding Chen,Yan Guo,Shu Feng Lei,Jin Tang Wang,Qi Zhou,Feng Pan,Yuan Chen,Zhi Xin Zhang,Shan-Shan Dong,Xiang Hong Xu,Han Yan,Xiao-Gang Liu,Chuan Qiu,Xue Zhen Zhu,Teng Chen,Meng Li,Hong Zhang,Liang Zhang,Betty M. Drees,James J. Hamilton,Christopher J. Papasian,Robert R. Recker,Xiaoping Song,Jing Cheng,Hong-Wen Deng,Hong-Wen Deng,Hong-Wen Deng +27 more
TL;DR: The association between CNV of UGT2B17 and OF was successfully replicated in an independent Chinese sample containing 399 cases with hip OF and 400 controls, suggesting the important contribution of CNV to the pathogenesis of osteoporosis.
Journal ArticleDOI
Genome-wide Association and Follow-Up Replication Studies Identified ADAMTS18 and TGFBR3 as Bone Mass Candidate Genes in Different Ethnic Groups
Dong Hai Xiong,Xiao-Gang Liu,Yan-Fang Guo,Li Jun Tan,Liang Wang,Bao Yong Sha,Zi Hui Tang,Feng Pan,Tie-Lin Yang,Xiang Ding Chen,Shu Feng Lei,Laura M. Yerges,Xue Zen Zhu,Victor W. Wheeler,Alan L. Patrick,C. H. Bunker,Yan Guo,Han Yan,Yu-Fang Pei,Yin Pin Zhang,Shawn Levy,Christopher J. Papasian,Peng Xiao,Y. Wang Lundberg,Robert R. Recker,Yao Zhong Liu,Yong Jun Liu,Joseph M. Zmuda,Hong-Wen Deng +28 more
TL;DR: The evidence supports that ADAMTS18 and TGFBR3 might underlie BMD determination in the major human ethnic groups.
Journal ArticleDOI
Genome-wide Association and Replication Studies Identified TRHR as an Important Gene for Lean Body Mass
Xiao-Gang Liu,Xiao-Gang Liu,Li Jun Tan,Shu Feng Lei,Shu Feng Lei,Yong Jun Liu,Hui Shen,Liang Wang,Liang Wang,Han Yan,Han Yan,Yan-Fang Guo,Dong Hai Xiong,Xiang Ding Chen,Feng Pan,Tie-Lin Yang,Yin Ping Zhang,Yin Ping Zhang,Yan Guo,Nelson L.S. Tang,Xue Zhen Zhu,Hong Yi Deng,Shawn Levy,Robert R. Recker,Christopher J. Papasian,Hong-Wen Deng,Hong-Wen Deng,Hong-Wen Deng +27 more
TL;DR: Results of this study support the TRHR gene as an important gene for LBM variation, together with the functional relevance of TRHR in muscle metabolism, by using Affymetrix 500K single-nucleotide polymorphism (SNP) arrays.
Journal ArticleDOI
Pathway-Based Genome-Wide Association Analysis Identified the Importance of Regulation-of-Autophagy Pathway for Ultradistal Radius BMD
Li-Shu Zhang,Yan-Fang Guo,Yan-Fang Guo,Yao Zhong Liu,Yong Jun Liu,Dong Hai Xiong,Xiao-Gang Liu,Liang Wang,Tie-Lin Yang,Shu Feng Lei,Yan Guo,Han Yan,Yu-Fang Pei,Feng Zhang,Christopher J. Papasian,Robert R. Recker,Hong-Wen Deng,Hong-Wen Deng,Hong-Wen Deng +18 more
TL;DR: This study supports the potential role of the ROA pathway in human wrist BMD variation and osteoporosis and identifies the regulation‐of‐autophagy (ROA) pathway that achieved the most significant result for association with UD BMD.
Journal ArticleDOI
Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis.
Yan Guo,Li Jun Tan,Shu Feng Lei,Tie-Lin Yang,Xiang Ding Chen,Feng Zhang,Yuan Chen,Feng Pan,Han Yan,Xiao-Gang Liu,Qing Tian,Zhi Xin Zhang,Qi Zhou,Chuan Qiu,Shan-Shan Dong,Xiang Hong Xu,Yan-Fang Guo,Xue Zhen Zhu,Shan Lin Liu,Xiang Li Wang,Xi Li,Yi Luo,Li Shu Zhang,Meng Li,Jin Tang Wang,Ting Wen,Betty M. Drees,James A. Hamilton,Christopher J. Papasian,Robert R. Recker,Xiaoping Song,Jing Cheng,Hong-Wen Deng +32 more
TL;DR: A SNP, rs13182402 within the ALDH7A1 gene on chromosome 5q31, was strongly associated with OF with evidence combined GWAS and replication studies, and was confirmed as consistently associated with hip BMD even across ethnic boundaries, in both Chinese and Caucasians.