C
Christopher S. Gilbert
Researcher at Lincoln's Inn
Publications - 11
Citations - 3856
Christopher S. Gilbert is an academic researcher from Lincoln's Inn. The author has contributed to research in topics: Gene & Enhancer. The author has an hindex of 7, co-authored 9 publications receiving 3825 citations. Previous affiliations of Christopher S. Gilbert include National Institute for Medical Research.
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Journal ArticleDOI
Induction of apoptosis in fibroblasts by c-myc protein
Gerard I. Evan,Andrew H. Wyllie,Christopher S. Gilbert,Trevor Littlewood,Hartmut Land,Mary W. Brooks,Catherine M. Waters,Linda Z. Penn,David C. Hancock +8 more
TL;DR: It is demonstrated that deregulated c-myc expression induces apoptosis in cells growth arrested by a variety of means and at various points in the cell cycle.
Journal ArticleDOI
Interferon response element of the human gene 6-16.
Andrew C.G. Porter,Y. Chernajovsky,Trevor Clive Dale,Christopher S. Gilbert,George R. Stark,Ian M. Kerr +5 more
TL;DR: The data suggest that a 39 bp sequence is sufficient to confer transcriptional inducibility and can account in large part for the response of 6‐16.
Journal ArticleDOI
Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells
M. Knight,M. Knight,P. J. Cayley,P. J. Cayley,R.H. Silverman,R.H. Silverman,Daniel H. Wreschner,Daniel H. Wreschner,Christopher S. Gilbert,Christopher S. Gilbert,R. E. Brown,R. E. Brown,Ian M. Kerr,Ian M. Kerr +13 more
TL;DR: In this paper, the authors describe convenient and sensitive radioimmune (RI) and radiobinding (RB) assays for core and 2-5A, which can also be detected using the RB assay, were not found in significant amounts.
Journal ArticleDOI
Construction by gene targeting in human cells of a "conditional' CDC2 mutant that rereplicates its DNA.
TL;DR: A novel gene targeting strategy for the genetic analysis of essential genes in mammalian cells and its use to study the role of the cell cycle control gene CDC2 in human cells is described.
Journal ArticleDOI
Affinity labelling and characterization of the ppp(A2'p)nA-dependent endoribonuclease from different mammalian sources.
TL;DR: It is concluded that the RNase and ppp(A2'p)nA binding activities are likely to reside in the same molecule.