C
Cindy Luongo
Researcher at National Institutes of Health
Publications - 54
Citations - 5629
Cindy Luongo is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Virus & Respiratory Syncytial Virus Vaccines. The author has an hindex of 30, co-authored 47 publications receiving 5298 citations. Previous affiliations of Cindy Luongo include University of Wisconsin-Madison.
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Journal ArticleDOI
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene.
Li Kuo Su,Kenneth W. Kinzler,Bert Vogelstein,Antoinette C. Preisinger,Amy R. Moser,Cindy Luongo,Karen A. Gould,William F. Dove +7 more
TL;DR: In this paper, a mouse lineage that exhibits an autosomal dominantly inherited predisposition to multiple intestinal neoplasia (Min) was described and linkage analysis showed that the murine homolog of the APC gene (mApc) was tightly linked to the Min locus.
Journal ArticleDOI
Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse.
William F. Dietrich,Eric S. Lander,Jennifer Smith,Amy R. Moser,Karen A. Gould,Cindy Luongo,Natalie Borenstein,William F. Dove +7 more
TL;DR: The genetic mapping of a locus that strongly modifies tumor number in Min/+ animals is reported, and this gene, Mom-1 (Modifier of Min-1), maps to distal chromosome 4 and controls about 50% of genetic variation in tumorNumber in two intraspecific backcrosses.
Journal Article
Loss of Apc+ in Intestinal Adenomas from Min Mice
TL;DR: Allelic loss at the ApC locus in spontaneously occurring intestinal adenomas from mice heterozygous for the ApcMin nonsense mutation was analyzed using a site-specific quantitative polymerase chain reaction assay.
Journal ArticleDOI
ApcMin: A mouse model for intestinal and mammary tumorigenesis
TL;DR: Min mice provide a good animal model for studying the role of Apc and interacting genes in the initiation and progression of intestinal and mammary tumorigenesis and can be increased in an age-specific manner by treatment with ethylnitrosourea (ENU).
Journal ArticleDOI
Corrections and Clarifications: Multiple Intestinal Neoplasia Caused By a Mutation in the Murine Homolog of the APC Gene
Li-Kuo Su,Kenneth W. Kinzler,Bert Vogelstein,Antonette C. Preisinger,Amy R. Moser,Cindy Luongo,Karen A. Gould,William F. Dove +7 more
TL;DR: In this paper, a mouse lineage that exhibits an autosomal dominantly inherited predisposition to multiple intestinal neoplasia (Min) was described and linkage analysis showed that the murine homolog of the APC gene (mApc) was tightly linked to the Min locus.