C
Cindy Luongo
Researcher at National Institutes of Health
Publications - 54
Citations - 5629
Cindy Luongo is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Virus & Respiratory Syncytial Virus Vaccines. The author has an hindex of 30, co-authored 47 publications receiving 5298 citations. Previous affiliations of Cindy Luongo include University of Wisconsin-Madison.
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Journal ArticleDOI
Homozygosity for the Min Allele of Apc Results in Disruption of Mouse Development Prior to Gastrulation
Amy R. Moser,Alex R. Shoemaker,Camille S. Connelly,Linda Clipson,Karen A. Gould,Cindy Luongo,William F. Dove,Pamela H. Siggers,Richard L. Gardner +8 more
TL;DR: Results indicate that functional Apc is required for normal growth of inner cell mass derivatives in embryos homozygous for ApcMin (Min), and development of the primitive ectoderm fails prior to gastrulation in Homozygous Min embryos.
Journal Article
Intestinal Neoplasia in the ApcMin Mouse: Independence from the Microbial and Natural Killer (beige Locus) Status
William F. Dove,Linda Clipson,Karen A. Gould,Cindy Luongo,David J. Marshall,Amy R. Moser,Michael A. Newton,Russell F. Jacoby +7 more
TL;DR: It is concluded that microbial status does not strongly alter the adenoma phenotype in this mouse model of familial adenomatous polyposis, and that C57BL/6-ApcMin/+ mice mutated at the beige locus, which controls natural killer activity, are also unaltered inAdenoma multiplicity.
Journal ArticleDOI
Studies of neoplasia in the min mouse
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A Chimeric A2 Strain of Respiratory Syncytial Virus (RSV) with the Fusion Protein of RSV Strain Line 19 Exhibits Enhanced Viral Load, Mucus, and Airway Dysfunction
Martin L. Moore,Michael H. Chi,Cindy Luongo,Nicholas W. Lukacs,Vasiliy V. Polosukhin,M.M. Huckabee,Dawn C. Newcomb,Ursula J. Buchholz,James E. Crowe,Kasia Goleniewska,John V. Williams,Peter L. Collins,R. Stokes Peebles +12 more
TL;DR: The F protein of RSV line 19 is identified as a factor that plays a role in pulmonary mucin expression in the setting of RSVs infection.
Journal ArticleDOI
RSV604, a Novel Inhibitor of Respiratory Syncytial Virus Replication
Joanna Chapman,Elizabeth Abbott,Dagmar Alber,Robert C. Baxter,Sian K. Bithell,Elisa Henderson,Malcolm Clive Carter,Phil Chambers,Ann Chubb,G. Stuart Cockerill,Peter L. Collins,Verity C. L. Dowdell,Sally J. Keegan,Richard D. Kelsey,Michael J. Lockyer,Cindy Luongo,Pilar Najarro,Raymond J. Pickles,Mark Simmonds,Debbie Taylor,Stan Tyms,Lara J. Wilson,Kenneth L. Powell +22 more
TL;DR: The discovery and initial development of RSV604, a novel benzodiazepine with submicromolar anti-RSV activity, which proved to be equipotent against all clinical isolates tested of both the A and B subtypes of the virus.