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Claire M. Gillan
Researcher at Trinity College, Dublin
Publications - 74
Citations - 5490
Claire M. Gillan is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Medicine & Cognition. The author has an hindex of 23, co-authored 52 publications receiving 4222 citations. Previous affiliations of Claire M. Gillan include New York University & University of California, San Francisco.
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Journal ArticleDOI
Neurocognitive endophenotypes of impulsivity and compulsivity: towards dimensional psychiatry
TL;DR: It is argued that a biological approach to psychiatry based on 'neurocognitive endophenotypes', whereby changes in behavioural or cognitive processes are associated with discrete deficits in defined neural systems, has important implications for the future classification of psychiatric disorders, genetics and therapeutics.
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Disorders of compulsivity: a common bias towards learning habits
Valerie Voon,K Derbyshire,Christian Rück,Michael A. Irvine,Yulia Worbe,Jesper Enander,Lrn Schreiber,Claire M. Gillan,Naomi A. Fineberg,Barbara J. Sahakian,Trevor W. Robbins,Neil A. Harrison,Jonathan Wood,Nathaniel D. Daw,Peter Dayan,Jon E. Grant,Edward T. Bullmore +16 more
TL;DR: The dysfunction in a common neurocomputational mechanism may underlie diverse disorders involving compulsion, and the habit formation bias is associated with lower gray matter volumes in caudate and medial orbitofrontal cortex.
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Disruption in the balance between goal-directed behavior and habit learning in obsessive-compulsive disorder
Claire M. Gillan,Martina Papmeyer,Sharon Morein-Zamir,Barbara J. Sahakian,Naomi A. Fineberg,Trevor W. Robbins,Sanne de Wit +6 more
TL;DR: The first experimental evidence for selective impairment in flexible and goal-directed behavioral control in patients with OCD is provided, forcing patients to rely instead on habits that can be triggered by stimuli regardless of the desirability of the consequences.
Journal ArticleDOI
Characterizing a psychiatric symptom dimension related to deficits in goal-directed control
Claire M. Gillan,Claire M. Gillan,Michal Kosinski,Robert Whelan,Elizabeth A. Phelps,Elizabeth A. Phelps,Elizabeth A. Phelps,Nathaniel D. Daw +7 more
TL;DR: Using large-scale online assessment of psychiatric symptoms and neurocognitive performance in two independent general-population samples, it was found that deficits in goal-directed control were most strongly associated with a symptom dimension comprising compulsive behavior and intrusive thought.
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New Developments in Human Neurocognition: Clinical, Genetic, and Brain Imaging Correlates of Impulsivity and Compulsivity
Naomi A. Fineberg,Samuel R. Chamberlain,Anna E. Goudriaan,Dan J. Stein,Louk J. M. J. Vanderschuren,Claire M. Gillan,Sameer Shekar,Philip Gorwood,Valerie Voon,Sharon Morein-Zamir,Damiaan Denys,Barbara J. Sahakian,F. Gerard Moeller,Trevor W. Robbins,Marc N. Potenza +14 more
TL;DR: New developments in the investigation of the neurocognition of impulsivity and compulsivity in humans are reviewed in order to advance the understanding of the pathophysiology of impulsive, compulsive, and addictive disorders and indicate new directions for research.