C
Claire N. Harrison
Researcher at Guy's and St Thomas' NHS Foundation Trust
Publications - 511
Citations - 24605
Claire N. Harrison is an academic researcher from Guy's and St Thomas' NHS Foundation Trust. The author has contributed to research in topics: Ruxolitinib & Myelofibrosis. The author has an hindex of 66, co-authored 424 publications receiving 19843 citations. Previous affiliations of Claire N. Harrison include St Thomas' Hospital & National Health Service.
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Journal ArticleDOI
Phase 3 Study Of Pomalidomide In Myeloproliferative Neoplasm (MPN)-Associated Myelofibrosis With RBC-Transfusion-Dependence
Ayalew Tefferi,Francesco Passamonti,Tiziano Barbui,Giovanni Barosi,Kebede H. Begna,Mario Cazzola,Francisco Cervantes,Konstanze Döhner,Heinz Gisslinger,Vikas Gupta,Wang Li,Claire N. Harrison,Jean-Jacques Kiladjian,Mary Frances McMullin,Alessandro Rambaldi,Gary J. Schiller,Alessandro M. Vannucchi,Ruben A. Mesa +17 more
TL;DR: There was no significant difference in rate or duration of RBC-transfusion-independence response to pomalidomide vs placebo despite using what were thought to be sensitive and specific entry- and response-criteria, and data suggest responses to pamalidomides and placebo differ but were not distinguished by the authors' response-Criteria.
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The Addition of Navitoclax to Ruxolitinib Demonstrates Efficacy within Different High-Risk Populations in Patients with Relapsed/Refractory Myelofibrosis
Naveen Pemmaraju,Jacqueline S. Garcia,Jalaja Potluri,Leanne Holes,Jason Harb,Paul M. Jung,Jessica E. Hutti,Josef T. Prchal,Srdan Verstovsek,Claire N. Harrison +9 more
TL;DR: This phase 2 study explored whether the presence of HMR, or the total number of genes mutated at study entry, correlated with clinical outcomes (SV reduction ≥35% [SVR35], reductions in TSS and BMF) and reductions in driver gene (JAK2 p.V617F and mutated CALR) variant allele frequency (VAF) following Nav plus Rux.
Journal ArticleDOI
Risk of COVID-19 death in cancer patients: an analysis from Guy's Cancer Centre and King's College Hospital in London.
Beth Russell,Charlotte Moss,Vallari Shah,Thinzar Ko Ko,Kieran Palmer,Rushan Sylva,Gincy George,Maria J. Monroy-Iglesias,Piers E.M. Patten,Piers E.M. Patten,Muhammed Mansour Ceesay,Reuben Benjamin,Reuben Benjamin,Victoria Potter,Antonio Pagliuca,Antonio Pagliuca,Sophie Papa,Sophie Papa,Sheeba Irshad,Sheeba Irshad,Paul Ross,James Spicer,James Spicer,Shahram Kordasti,Shahram Kordasti,Danielle Crawley,Danielle Crawley,Harriet Wylie,Fidelma Cahill,Anna Haire,Kamarul Zaki,Ailsa Sita-Lumsden,Debra H. Josephs,Debra H. Josephs,Deborah Enting,Deborah Enting,Angela Swampillai,Elinor J. Sawyer,Elinor J. Sawyer,Andrea D'Souza,Simon Gomberg,Claire N. Harrison,Paul Fields,David Wrench,Anne Rigg,Richard Sullivan,Austin G. Kulasekararaj,Austin G. Kulasekararaj,Saoirse Dolly,Mieke Van Hemelrijck,Mieke Van Hemelrijck +50 more
TL;DR: In this paper, a Cox proportional hazards regression was performed to identify which factors were associated with COVID-19-related death in cancer patients, including Haematological cancer, longer-established cancer diagnosis, dyspnoea at diagnosis and raised CRP.
Reimagining the 'social' in the nutrition sciences.
TL;DR: It is called for researchers, educators, policy makers and practitioners alike to re-imagine the role and purpose of social science enquiry that could enable the delivery of more socially engaged nutrition sciences.
Journal ArticleDOI
The management and outcome of four pregnancies in women with idiopathic myelofibrosis
Sameer Tulpule,Susan Bewley,Susan Robinson,Deepti Radia,Catherine Nelson-Piercy,Claire N. Harrison +5 more
TL;DR: The outcome and management of four further pregnancies in two patients with untreated PMF attending the authors' institution are described, including a full thrombophilia screen, BCR/ABL1, JAK2 and MPLW 515L/K status.