C
Claude Rouillard
Researcher at Laval University
Publications - 67
Citations - 2948
Claude Rouillard is an academic researcher from Laval University. The author has contributed to research in topics: Dopamine & Dopamine receptor. The author has an hindex of 31, co-authored 66 publications receiving 2795 citations. Previous affiliations of Claude Rouillard include Wayne State University & Max Planck Society.
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Journal ArticleDOI
Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons
Banafsheh Kadkhodaei,Takehito Ito,Eliza Joodmardi,Bengt Mattsson,Claude Rouillard,Manolo Carta,Shin-ichi Muramatsu,Chiho Sumi-Ichinose,Takahide Nomura,Daniel Metzger,Pierre Chambon,Eva Lindqvist,Nils-Göran Larsson,Lars Olson,Anders Björklund,Hiroshi Ichinose,Thomas Perlmann +16 more
TL;DR: The results show that developmental pathways play key roles for the maintenance of terminally differentiated neurons and suggest that disrupted function of Nurr1 and other developmental transcription factors may contribute to neurodegenerative disease.
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17β-estradiol at a physiological dose acutely increases dopamine turnover in rat brain
TL;DR: In ovariectomized rats with a unilateral lesion of the entopeduncular nucleus, the same dose of 17 beta-estradiol induced a postural deviation to the lesioned side with a maximum at 30 min, and very small doses of estradiol were able to increase dopamine turnover.
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Rotenone induces non-specific central nervous system and systemic toxicity
Nicolas P. Lapointe,Michel St-Hilaire,Maria-Grazia Martinoli,Julie Blanchet,Peter V Gould,Claude Rouillard,Francesca Cicchetti +6 more
TL;DR: Overall, the effects of rotenone toxicity are widespread, and subcutaneous administration of this toxin does not provide the neuropathological and behavioral basis for a relevant and reliable PD model.
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Differences between subacute and chronic MPTP mice models: investigation of dopaminergic neuronal degeneration and α‐synuclein inclusions
Claire Gibrat,Martine Saint-Pierre,Mélanie Bousquet,Daniel Lévesque,Claude Rouillard,Francesca Cicchetti +5 more
TL;DR: Overall, it is found that the 14‐day chronic MPTP i.p. infusion reproduces more accurately the pathological characteristics of early stage Parkinson’s disease.
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Dorsal raphe stimulation differentially modulates dopaminergic neurons in the ventral tegmental area and substantia nigra.
Julie Gervais,Claude Rouillard +1 more
TL;DR: The effects of electrical stimulation of the DRN on the spontaneous activity of substantia nigra pars compacta (SNpc) and ventral tegmental area (VTA) DA neurons in anesthetized rats are investigated and it is suggested that non‐5‐HT inputs from DR can also modulate mesencephalic DA neurons.