Journal ArticleDOI
17β-estradiol at a physiological dose acutely increases dopamine turnover in rat brain
Reads0
Chats0
TLDR
In ovariectomized rats with a unilateral lesion of the entopeduncular nucleus, the same dose of 17 beta-estradiol induced a postural deviation to the lesioned side with a maximum at 30 min, and very small doses of estradiol were able to increase dopamine turnover.About:
This article is published in European Journal of Pharmacology.The article was published on 1985-11-05. It has received 201 citations till now. The article focuses on the topics: Homovanillic acid & Dopamine releasing agent.read more
Citations
More filters
Journal ArticleDOI
Estrogen actions in the central nervous system.
Bruce S. McEwen,Stephen E. Alves +1 more
TL;DR: This work has shown that estrogens, Neuroprotection, and Alzheimer’s Disease are intertwined and that the effects of estrogens on learning and memory are determined by the mechanism of action of the hormone.
Journal ArticleDOI
Sex differences in drug abuse
Jill B. Becker,Ming Hu +1 more
TL;DR: In this review, sex differences in drug abuse are discussed for humans and in animal models, and the possible neuroendocrine mechanisms mediating these sex differences are discussed.
Journal ArticleDOI
Gender differences in dopaminergic function in striatum and nucleus accumbens.
TL;DR: It is suggested that hormonal modulation of the striatum may have evolved to facilitate reproductive success in female rats by enhancing pacing behavior and has important implications for gender differences in susceptibility to addiction to the psychomotor stimulants.
Journal ArticleDOI
Biological basis of sex differences in drug abuse: preclinical and clinical studies.
TL;DR: Preclinical and clinical studies indicate that ovarian hormones, particularly estrogen, play a role in producing sex differences in drug abuse, and it is necessary to provide information on how to design more effective drug abuse treatment programs and resources that are sex specific.
Journal ArticleDOI
Dopamine receptors: Molecular biology, biochemistry and behavioural aspects
TL;DR: Progress has been made in understanding the function of DA-containing discrete brain nuclei and the functional consequence of the DA's interaction with other neurotransmitters, and some of the latest advances in these various areas are explored.
References
More filters
Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Extension of multiple range tests to group means with unequal numbers of replications
Abstract: In many fields of research, one is faced with the task of comparing the effects of treatments which have been replicated unequally. This happens for a number of reasons. In an experiment on animals, some may get sick and have to be removed from the experiment. In some experiments, the amount of material available for certain treatments may not be as much as for other treatments. If the experimenter has specified orthogonal contrasts that he is interested in before he runs the experiment, one can test the various treatment effects by an F-test after the treatment sum of squares has been partitioned into individual degrees of freedom for each orthogonal contrast. If the experimenter has not specified orthogonal contrasts, one is faced with the problem of deciding which treatments are significantly different. Several writers, including Duncan, Keuls, Newman, and Tukey, have developed multiple range tests to show differences among treatments that have been replicated the same number of times and when nothing was specified concerning the treatments. Duncan [1] compares the above methods and gives citations. This extension to unequal numbers of replications will be exemplified with reference to Duncan's "New Multiple Range Test," but is applicable to any of the above writers' tests; all one has to do is use their tabled ranges. In Duncan's test for an equal number of replications, the difference between any two ranked means is significant if the difference exceeds a shortest significant range. This shortest significant range is designated by R, and is obtained by multiplying the standard error of a mean, s,, by a given value, zn2, obtained from a table of significant studentized ranges which Duncan has tabled for both the 5% and 1% test. In Duncan's terminology, n2 is the degrees of freedom of the error mean square and p = 1, 2, * *, t is the number of means concerned. Consider an experiment with five treatments, A, B. C, D, and E, each replicated n times. Suppose on ranking the means from low to high one obtains
Journal ArticleDOI
The control of progesterone secretion during the estrous cycle and early pseudopregnancy in the rat: prolactin, gonadotropin and steroid levels associated with rescue of the corpus luteum of pseudopregnancy.
TL;DR: It is suggested that nocturnal surge on D-2, PROLACTin is the major Luteotropic stimulus which transforms and estrous cycle into pseudopregnancy by prolonging progesterone secretion from the corpus luteum.
Related Papers (5)
Estrogen rapidly potentiates amphetamine-induced striatal dopamine release and rotational behavior during microdialysis.
Estrogen Regulation of Dopamine Release in the Nucleus Accumbens: Genomic‐and Nongenomic‐Mediated Effects
Tina L. Thompson,Robert L. Moss +1 more