Claudia Gärtner

TL;DR: This paper presents an overview of existing polymer microfabrication technologies for microfluidic applications, namely replication methods such as hot embossing, injection molding and casting, and the technologies necessary to fabricate the molding masters.

TL;DR: This review will introduce the currently relevant microfabrication technologies such as replication methods like hot embossing, injection molding, microthermoforming and casting as well as photodefining methods like lithography and laser ablation for microfluidic systems and discuss academic and industrial considerations for their use.

TL;DR: It is concluded that the perfused liver organoid shares relevant morphological and functional characteristics with the human liver and represents a new in vitro research tool to study human hepatocellular physiology at the cellular level under conditions close to the physiological situation.

TL;DR: The need for low-cost microfabrication technologies in modern life-sciences is described in this article, where the authors compare the replication technologies, hot embossing and micro-injection molding and give an overview over the technologies used for fabrication of the replication masters.

TL;DR: A microsystem integrating electrochemical detection for the simultaneous detection of protein markers of breast cancer is reported and has been validated using real patient serum samples and excellent correlation with ELISA results obtained.