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Cláudia Silva
Researcher at University of Coimbra
Publications - 23
Citations - 1062
Cláudia Silva is an academic researcher from University of Coimbra. The author has contributed to research in topics: Polyelectrolyte & Corneocyte. The author has an hindex of 15, co-authored 23 publications receiving 898 citations. Previous affiliations of Cláudia Silva include University of Wuppertal.
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Oral films: Current status and future perspectives: I - Galenical development and quality attributes.
TL;DR: This pharmaceutical form with a blustering beginning as a breath freshener had an emergent entrance in the Rx market proving its reliable value, and is described and explores the oral film technology from its main component, the polymeric matrices, to the new and possible market applications.
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Films based on chitosan polyelectrolyte complexes for skin drug delivery: Development and characterization
TL;DR: In this paper, a chitosan-based polyelectrolyte complexes (PEC) was developed and optimized in order to obtain films possessing the optimal functional properties (flexibility, resistance, water vapour transmission rate and bioadhesion) to be applied on skin.
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Stratum corneum hydration: phase transformations and mobility in stratum corneum, extracted lipids and isolated corneocytes.
Cláudia Silva,Daniel Topgaard,Vitaly Kocherbitov,João Sousa,Alberto A. C. C. Pais,Emma Sparr +5 more
TL;DR: There is a substantial swelling both of SC lipids, the corneocytes and the intact SC at high RH, and it is speculated that the lipid re-organization is responsible for the hydration-induced variations in SC permeability.
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Quality by design in pharmaceutical manufacturing: A systematic review of current status, challenges and future perspectives.
TL;DR: This review aims to analyse the current state of implementation of QbD methodologies and tools in the pharmaceutical industry, extracting patterns and trends and identifying gaps and opportunities that may be considered to improveQbD adoption.
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Interplay of electrostatic and hydrophobic effects with binding of cationic gemini surfactants and a conjugated polyanion: experimental and molecular modeling studies.
Hugh D. Burrows,María J. Tapia,Cláudia Silva,Alberto A. C. C. Pais,Sofia M. Fonseca,João Pina,J. Sérgio Seixas de Melo,Yujie Wang,Eduardo F. Marques,Matti Knaapila,Andrew P. Monkman,Vasil M. Garamus,Swapna Pradhan,Ullrich Scherf +13 more
TL;DR: Qualitatively, with the intermediate 12-5-12 and 12-6-12 systems, the optimum balance is observed between Coulombic and hydrophobic interactions, explaining their strong fluorescence enhancement.