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Colette Dissous

Researcher at Pasteur Institute

Publications -  121
Citations -  4172

Colette Dissous is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Schistosoma mansoni & Receptor tyrosine kinase. The author has an hindex of 37, co-authored 120 publications receiving 3977 citations. Previous affiliations of Colette Dissous include University of Giessen & French Institute of Health and Medical Research.

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A multienzyme network functions in intestinal protein digestion by a platyhelminth parasite.

TL;DR: Defining the role of each of these major enzymes provides a clearer understanding of the function of a complex protease network that is conserved throughout invertebrate evolution and provides insights into which of these proteases are logical targets for development of chemotherapy for schistosomiasis, a major global health problem.
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An anti-idiotype vaccine against experimental schistosomiasis

TL;DR: Rat monoclonal anti-idiotype antibodies were produced against IPLSm1 (AB1), and rats immunized with AB2 demonstrated marked protection to a challenge infection, following Jerne's network theory.
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Immunosuppression in the definitive and intermediate hosts of the human parasite Schistosoma mansoni by release of immunoactive neuropeptides.

TL;DR: Evidence supporting the concept that the parasitic trematode Schistosoma mansoni may escape immune reactions from its vertebrate (man) or invertebrate (the freshwater snail Biomphalaria glabrata) hosts by using signal molecules it has in common with these hosts was obtained by the following experiments.
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Schistosoma mansoni shares a protective carbohydrate epitope with keyhole limpet hemocyanin.

TL;DR: The deglycosylation of KLH completely abolishes its immunological and functional KLH properties, indicating the participation of an oligosaccharidic epitope of the native KLH that is also recognized by the sera of S. mansoni-infected patients.
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Snail Control Strategies for Reduction of Schistosomiasis Transmission

TL;DR: The efficacy of environmental management and the use of molluscicides and biological agents to control snail populations are reviewed and the development of diagnostic tests, based on the detection of parasite antigens or specific parasite DNA sequences in snail tissues, are described.