Cosimo Sperti

TL;DR: It is suggested that patient characteristics and tumour findings rather than operative procedures affect long‐term survival after resection for pancreatic carcinoma.

TL;DR: It appears that surgery alone is an inadequate treatment for cure in patients with pancreatic carcinoma, and effective adjuvant therapies are needed to improve locoregional control of pancreatic cancer after surgical resection.

TL;DR: This study supports an initial conservative management in the majority of patients with SCN, and suggests surgical treatment should be proposed only for diagnosis remaining uncertain after complete workup, significant and related symptoms or exceptionally when exists concern with malignancy.

TL;DR: The survival of patients with pancreatic cancer depends mainly on tumor stage, but it is also affected by the number of circulating lymphocytes, suggesting that the immune system plays an important role in pancreatic adenocarcinoma immunosurveillance and immunoediting.

TL;DR: Results suggest that CCL2 could be a relevant negative regulator of pancreatic cancer progression and other proinflammatory cytokines such as tumor necrosis factor alpha and IFN-gamma appeared able to induce apoptosis and to reduce the proliferative rate of pancreating cancer.