D
Darwin L. Conwell
Researcher at The Ohio State University Wexner Medical Center
Publications - 356
Citations - 10518
Darwin L. Conwell is an academic researcher from The Ohio State University Wexner Medical Center. The author has contributed to research in topics: Pancreatitis & Medicine. The author has an hindex of 46, co-authored 318 publications receiving 8490 citations. Previous affiliations of Darwin L. Conwell include Cleveland Clinic & Boston Children's Hospital.
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Journal ArticleDOI
The early prediction of mortality in acute pancreatitis: a large population-based study
TL;DR: The BISAP is a simple and accurate method for the early identification of patients at increased risk for in-hospital mortality in acute pancreatitis.
Journal ArticleDOI
Lactated Ringer's solution reduces systemic inflammation compared with saline in patients with acute pancreatitis.
Bechien U. Wu,James Q. Hwang,Timothy H. Gardner,Kathryn Repas,Ryan Delee,Song Yu,Benjamin N. Smith,Peter A. Banks,Darwin L. Conwell +8 more
TL;DR: Patients with acute pancreatitis who were resuscitated with lactated Ringer's solution had reduced systemic inflammation compared with those who received saline.
Journal ArticleDOI
Gastroenterologist-administered propofol versus meperidine and midazolam for advanced upper endoscopy: a prospective, randomized trial.
John J. Vargo,Gregory Zuccaro,John A. Dumot,J.Brad Morrow,Darwin L. Conwell,Patricia Trolli,Kenneth M. Shermock,Walter G. Maurer +7 more
TL;DR: Gastroenterologist-administered propofol using monitoring with capnography is similar to meperidine/midazolam for both physiological outcomes and patient/endoscopist satisfaction, and leads to significantly improved recovery of baseline activity and food intake 24 hours after the procedure.
Journal ArticleDOI
American Pancreatic Association practice guidelines in chronic pancreatitis evidence-based report on diagnostic guidelines
Darwin L. Conwell,Linda S. Lee,Dhiraj Yadav,Daniel S. Longnecker,Frank H. Miller,Koenraad J. Mortele,Michael J. Levy,Richard S. Kwon,John G. Lieb,Tyler Stevens,Phillip P. Toskes,Timothy B. Gardner,Andres Gelrud,Bechien U. Wu,Chris E. Forsmark,Santhi Swaroop Vege +15 more
TL;DR: A diagnostic (STEP-wise; survey, tomography, endoscopy, and pancreas function testing) algorithm is proposed that proceeds from a noninvasive to a more invasive approach and a nomenclature is suggested to further characterize patients with established chronic pancreatitis based on TIGAR-O for uniformity across future multicenter research collaborations.
Journal ArticleDOI
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis
David C. Whitcomb,Jessica LaRusch,Alyssa M. Krasinskas,Lambertus Klei,Jill P. Smith,Randall E. Brand,John P. Neoptolemos,Markus M. Lerch,Matt Tector,Bimaljit S. Sandhu,Nalini M. Guda,Lidiya Orlichenko,Samer Alkaade,Stephen T. Amann,Michelle A. Anderson,John Baillie,Peter A. Banks,Darwin L. Conwell,Gregory A. Cote,Peter B. Cotton,James A. DiSario,Lindsay A. Farrer,Chris E. Forsmark,Marianne Johnstone,Timothy B. Gardner,Andres Gelrud,William Greenhalf,Jonathan L. Haines,Douglas J. Hartman,Robert A. Hawes,Christopher Lawrence,Michele D. Lewis,Julia Mayerle,Richard Mayeux,Nadine M. Melhem,Mary E. Money,Thiruvengadam Muniraj,Georgios I. Papachristou,Margaret A. Pericak-Vance,Joseph Romagnuolo,Gerard D. Schellenberg,Stuart Sherman,Peter Simon,Vijay P. Singh,Adam Slivka,Donna B. Stolz,Robert Sutton,Frank Ulrich Weiss,C. Mel Wilcox,Narcis O. Zarnescu,Stephen R. Wisniewski,Michael R. O'Connell,Michelle L. Kienholz,Kathryn Roeder,M. Michael Barmada,Dhiraj Yadav,Bernie Devlin,Marilyn S. Albert,Roger L. Albin,Roger L. Albin,Liana G. Apostolova,Steven E. Arnold,Clinton T. Baldwin,Robert Barber,Lisa L. Barnes,Thomas G. Beach,Gary W. Beecham,Duane Beekly,David A. Bennett,Eileen H. Bigio,Thomas D. Bird,Deborah Blacker,Adam L. Boxer,James R. Burke,Joseph D. Buxbaum,Nigel J. Cairns,Laura B. Cantwell,Chuanhai Cao,Regina M. Carney,Steven L. Carroll,Helena C. Chui,David G. Clark,David H. Cribbs,Elizabeth Crocco,Carlos Cruchaga,Charles DeCarli,F. Yesim Demirci,Malcolm B. Dick,Dennis W. Dickson,Ranjan Duara,Nilufer Ertekin-Taner,Kelley Faber,Kenneth B. Fallon,Martin R. Farlow,Steven H. Ferris,Tatiana Foroud,Matthew P. Frosch,Douglas Galasko,Mary Ganguli,Marla Gearing,Daniel H. Geschwind,Bernardino Ghetti,John R. Gilbert,Sid Gilman,Jonathan D. Glass,Alison Goate,Neill R. Graff-Radford,Robert C. Green,John H. Growdon,Hakon Hakonarson,Kara L. Hamilton-Nelson,Ronald L. Hamilton,Lindy E. Harrell,Elizabeth Head,Lawrence S. Honig,Christine M. Hulette,Bradley T. Hyman,Gregory A. Jicha,Lee-Way Jin,Gyungah Jun,M. Ilyas Kamboh,Anna Karydas,Jeffrey Kaye,Jeffrey Kaye,Ronald C. Kim,Edward H. Koo,Neil W. Kowall,Joel H. Kramer,Patricia L. Kramer,Walter A. Kukul,Frank M. LaFerla,James J. Lah,James B. Leverenz,Allan I. Levey,Ge Li,Chiao-Feng Lin,Andrew P. Lieberman,Oscar L. Lopez,Kathryn L. Lunetta,Constantine G. Lyketsos,Wendy J. Mack,Daniel C. Marson,Eden R. Martin,Frank Martiniuk,Deborah C. Mash,Eliezer Masliah,Ann C. McKee,M.-Marsel Mesulam,Bruce L. Miller,Carol A. Miller,Joshua W. Miller,Thomas J. Montine,John C. Morris,Jill R. Murrel,Adam C. Naj,Adam C. Naj,John M Olichney,Joseph E. Parisi,Elaine R. Peskind,Ronald C. Petersen,Aimee Pierce,Wayne W. Poon,Huntington Potter,Joseph F. Quinn,Ashok Raj,Murray A. Raskind,Eric M. Reiman,Barry Reisberg,Christiane Reitz,John M. Ringman,Erik D. Roberson,Howard J. Rosen,Roger N. Rosenberg,Mary Sano,Andrew J. Saykin,Julie A. Schneider,Lon S. Schneider,William W. Seeley,Amanda Smith,Joshua A. Sonnen,Salvatore Spina,Robert S. Stern,Rudolph E. Tanzi,John Q. Trojanowski,Juan C. Troncoso,Juan C. Troncoso,Debby W. Tsuang,Otto Valladares,Vivianna M. Van Deerlin,Linda J. Van Eldik,Badri N. Vardarajan,Harry V. Vinters,Jean Paul Vonsatte,Li-San Wang,Sandra Weintraub,Kathleen A. Welsh-Bohmer,Jennifer Williamson,Randall L. Woltjer,Clinton B. Wright,Steven G. Younkin,Chang En Yu,Lei Yu +201 more
TL;DR: Two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 are reported and could partially explain the high frequency of alcohol-related pancreatitis in men.