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Lorenzo Piemonti

Researcher at Vita-Salute San Raffaele University

Publications -  328
Citations -  19442

Lorenzo Piemonti is an academic researcher from Vita-Salute San Raffaele University. The author has contributed to research in topics: Transplantation & Islet. The author has an hindex of 62, co-authored 290 publications receiving 15614 citations. Previous affiliations of Lorenzo Piemonti include George Mason University & University of Milano-Bicocca.

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Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

Paul Bastard, +140 more
- 23 Oct 2020 - 
TL;DR: A means by which individuals at highest risk of life-threatening COVID-19 can be identified is identified, and the hypothesis that neutralizing auto-Abs against type I IFNs may underlie critical CO VID-19 is tested.
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Vitamin D3 Affects Differentiation, Maturation, and Function of Human Monocyte-Derived Dendritic Cells

TL;DR: The data suggest that 1α,25-(OH)2D3 may modulate the immune system, acting at the very first step of the immune response through the inhibition of DC differentiation and maturation into potent APC.
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IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages.

TL;DR: Cells cultured in the presence of IL‐10 were poor stimulators of allogeneic cord blood T cells in mixed lymphocyte reaction (MLR) and presented tetanus toxin to specific T cell lines with much less efficiency than control DC.
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Pancreatic Endocrine Tumors: Expression Profiling Evidences a Role for AKT-mTOR Pathway

TL;DR: The results strongly support a role for PI3K/Akt/mTOR pathway in PET, which ties in with the fact that mTOR inhibitors have reached phase III trials in neuroendocrine tumors and raises the potential for SSTR expression to be evaluated as a marker of response to somatostatin analogs.