Craig H. Duncan

TL;DR: It is demonstrated that a portion of this highly conserved segment of repetitive mamalian DNA sequence is similar to a sequence found within a low molecular weight RNA that hydrogen-bonds to poly(A)-terminated RNA molecules of Chinese hamsters and a sequence that forms half of a perfect inverted repeat near the origin of DNA replication in papovaviruses.

TL;DR: Cloned human DNA fragments containing globin genes are transcribed in vitro to form discrete RNA species to study the role of globin in EMT and its role in wound healing.

TL;DR: The template for RNA polymerase III in vitro transcription found on the human DNA clone pJP53 was shown to enclose a member of the Alu famiy of interspersed repetitive DNA sequences to be mapped onto its template in greater detail by comparison of the template DNA sequence to the base composition of the Tl ribonuclease digestion products of the in vitro transcript.

TL;DR: The data indicate the repetitive DNA sequences, members of the Alu family of interpersed 300 bp reiterated DNA, are imbedded in both templates and the RNAs transcribed from them are composed of an entire AlU family sequence.

TL;DR: The nucleotide sequences of two cloned fragments of human DNA which function as templates for RNA polymerase III in vitro confirm their identities as members of the Alu family of human interspersed repetitive DNA sequences, and evidence indicates that the human Alufamily resembles a partial duplication of the murine B1 sequence.