P. A. Biro

TL;DR: It is demonstrated that a portion of this highly conserved segment of repetitive mamalian DNA sequence is similar to a sequence found within a low molecular weight RNA that hydrogen-bonds to poly(A)-terminated RNA molecules of Chinese hamsters and a sequence that forms half of a perfect inverted repeat near the origin of DNA replication in papovaviruses.

TL;DR: Nucleotide sequence analysis of cloned gene fragments from a patient with homozygous beta+-thalassemia permitted identification of a single base change in the body of the small intervening sequence, which suggests a mechanism for defective posttranscriptional processing of beta globin mRNA precursor molecules in beta--halassemia.

TL;DR: Cloned human DNA fragments containing globin genes are transcribed in vitro to form discrete RNA species to study the role of globin in EMT and its role in wound healing.

TL;DR: Two unique genomic clones designated JY B3.2 and JY 158, isolated from the human lymphoblastoid cell line JY, were shown to contain gene sequences capable of directing expression of an HLA-A, -B, -C determinant.

TL;DR: This brief review has been on the analysis of the sequence diversity among various class I genes and their functional implications, and the availability of complete nucleotide sequences of 7 different genes representing different loci allowed us to derive a consensus sequence.