T
Thomas P. Toomey
Researcher at Rockefeller University
Publications - 2
Citations - 583
Thomas P. Toomey is an academic researcher from Rockefeller University. The author has contributed to research in topics: Consensus sequence & Interspersed repeat. The author has an hindex of 2, co-authored 2 publications receiving 582 citations.
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Journal ArticleDOI
Ubiquitous, interspersed repeated sequences in mammalian genomes
Warren Jelinek,Thomas P. Toomey,Leslie A. Leinwand,Craig H. Duncan,P. A. Biro,Prabhakara V. Choudary,Sherman M. Weissman,Carol M. Rubin,Catherine M. Houck,Prescott L. Deininger,Carl W. Schmid +10 more
TL;DR: It is demonstrated that a portion of this highly conserved segment of repetitive mamalian DNA sequence is similar to a sequence found within a low molecular weight RNA that hydrogen-bonds to poly(A)-terminated RNA molecules of Chinese hamsters and a sequence that forms half of a perfect inverted repeat near the origin of DNA replication in papovaviruses.
Journal ArticleDOI
The Chinese hamster Alu-equivalent sequence: a conserved highly repetitious, interspersed deoxyribonucleic acid sequence in mammals has a structure suggestive of a transposable element.
TL;DR: A consensus sequence has been determined for a major interspersed deoxyribonucleic acid repeat in the genome of Chinese hamster ovary cells (CHO cells) and it is likely that the Alu sequence dispersed throughout the mammalian genome by transposition.