C
Cristina Antinozzi
Researcher at Sapienza University of Rome
Publications - 40
Citations - 520
Cristina Antinozzi is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 12, co-authored 29 publications receiving 325 citations. Previous affiliations of Cristina Antinozzi include Foro Italico University of Rome & University of Rome Tor Vergata.
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Journal ArticleDOI
Reduced Proficiency in Homologous Recombination Underlies the High Sensitivity of Embryonal Carcinoma Testicular Germ Cell Tumors to Cisplatin and Poly (ADP-Ribose) Polymerase Inhibition
Francesca Cavallo,Grazia Graziani,Cristina Antinozzi,Darren R. Feldman,Jane Houldsworth,George J. Bosl,Raju S.K. Chaganti,Mary Ellen Moynahan,Maria Jasin,Marco Barchi +9 more
TL;DR: The results point to a reduced proficiency of HR repair as a source of sensitivity of ECs to ICL-inducing agents and PARP inhibitor monotherapy, and suggest that pharmacological inhibition of PARP can be exploited to target the stem cell component of the TGCTs (namely ECs) and to enhance the sensitivity of cisplatin-resistantTGCTs to standard treatments.
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Phosphodiesterase Type 5 Inhibitor Sildenafil Decreases the Proinflammatory Chemokine CXCL10 in Human Cardiomyocytes and in Subjects with Diabetic Cardiomyopathy
Luigi Di Luigi,Clarissa Corinaldesi,Marta Colletti,Sabino Scolletta,Cristina Antinozzi,Gabriella B. Vannelli,Elisa Giannetta,Daniele Gianfrilli,Andrea M. Isidori,Silvia Migliaccio,Noemi Poerio,Maurizio Fraziano,Andrea Lenzi,Clara Crescioli +13 more
TL;DR: T helper 1 (Th1) type cytokines and chemokines are bioactive mediators in inflammation underling several diseases and co-morbid conditions, such as cardiovascular and metabolic disorders and sildenafil could be a pharmacologic tool to control CXCL10-associated inflammation in diabetic cardiomyopathy.
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Vitamin D in autoimmune rheumatic diseases: A view inside gender differences.
TL;DR: The main vitamin D immunoregulatory properties are summarized with some sex hormone‐driven immune activities, in females and males immune systems, and Topics onto vitamin D receptor agonists as potential therapeutic agents in rheumatic disease are addressed.
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Exosomes in Systemic Sclerosis: Messengers Between Immune, Vascular and Fibrotic Components?
Marta Colletti,Angela Galardi,Maria De Santis,Giacomo Maria Guidelli,Angela Di Giannatale,Luigi Di Luigi,Cristina Antinozzi +6 more
TL;DR: A possible role of exosomes in SSc pathogenesis is indicated and their potential use as diagnostic and prognostic biomarkers, as well as therapeutic tools, are suggested.
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Association of circulating CXCL10 and CXCL11 with systemic sclerosis.
Clara Crescioli,Clarissa Corinaldesi,Clarissa Corinaldesi,Valeria Riccieri,Valeria Raparelli,Massimiliano Vasile,Francesco Del Galdo,Guido Valesini,Andrea Lenzi,Stefania Basili,Cristina Antinozzi +10 more
TL;DR: This study investigated whether the shift from very early diagnosis of SSc (VEDOSS), when vasculopathy and fibrosis are at very low degree, to definite SSc elicits serum CXCL10/CXCL11 modifications.