C
Cristina Matteo
Researcher at Mario Negri Institute for Pharmacological Research
Publications - 19
Citations - 248
Cristina Matteo is an academic researcher from Mario Negri Institute for Pharmacological Research. The author has contributed to research in topics: Medicine & Asparaginase. The author has an hindex of 7, co-authored 17 publications receiving 116 citations.
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Journal ArticleDOI
Venetoclax penetrates in cerebrospinal fluid and may be effective in chronic lymphocytic leukemia with central nervous system involvement.
Gianluigi Reda,Ramona Cassin,Gabriela Dovrtelova,Cristina Matteo,Juri Alessandro Giannotta,Maurizio D'Incalci,Agostino Cortelezzi,Massimo Zucchetti +7 more
TL;DR: Venetoclax, a selective inhibitor of BCL2, has shown promising efficacy in chronic lymphocytic leukemia (CLL) both as single agent or in combination therapy.
Journal ArticleDOI
Electrostatic Intraperitoneal Aerosol Delivery of Nanoparticles: Proof of Concept and Preclinical Validation.
Leen Van de Sande,Mohammad Rahimi-Gorji,Silvia Giordano,Enrico Davoli,Cristina Matteo,Sönke Detlefsen,Sönke Detlefsen,Katharina D'Herde,Helena Braet,Molood Shariati,Katrien Remaut,Feifan Xie,Charlotte Debbaut,Ghader Ghorbaniasl,Sarah Cosyns,Wouter Willaert,Wim Ceelen +16 more
TL;DR: Electrostatic precipitation (EP) enhances spatial homogeneity and tissue uptake after intraperitoneal nebulization of anticancer NPs and leads to more homogenous peritoneal tissue concentrations of Nab‐PTX, in parallel with higher plasma concentrations.
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A novel oral micellar fenretinide formulation with enhanced bioavailability and antitumour activity against multiple tumours from cancer stem cells.
Isabella Orienti,Valentina Salvati,Valentina Salvati,Giovanni Sette,Giovanni Sette,Massimo Zucchetti,Lucilla Bongiorno-Borbone,Angelo Peschiaroli,Lello Zolla,Federica Francescangeli,Mariella Ferrari,Cristina Matteo,Ezia Bello,Antonio Di Virgilio,Mario Falchi,Maria Laura De Angelis,Marta Baiocchi,Gerry Melino,Ruggero De Maria,Ann Zeuner,Adriana Eramo +20 more
TL;DR: Results indicate Bio-nFeR as a novel anticancer agent with low toxicity and high activity against tumourigenic cells, potentially useful for the treatment of solid tumours of multiple origin.
Journal ArticleDOI
Asparagine levels in the cerebrospinal fluid of children with acute lymphoblastic leukemia treated with pegylated-asparaginase in the induction phase of the AIEOP-BFM ALL 2009 study
Carmelo Rizzari,Claudia Lanvers-Kaminsky,Maria Grazia Valsecchi,Andrea Ballerini,Cristina Matteo,Joachim Gerss,Gudrun Wuerthwein,Daniela Silvestri,Antonella Colombini,Valentino Conter,Andrea Biondi,Martin Schrappe,Anja Moericke,Martin Zimmermann,Arend von Stackelberg,Christin Linderkamp,Michael C. Frühwald,Sabine Legien,Andishe Attarbaschi,Bettina Reismüller,David C. Kasper,Petr Smisek,Jan Stary,Luciana Vinti,Elena Barisone,Rosanna Parasole,Concetta Micalizzi,Massimo Zucchetti,Joachim Boos +28 more
TL;DR: Cerebrospinal fluid asparagine levels were reduced during pegylated-asparaginase treatment, but complete depletion was only observed in a minority of patients, strengthening the observations of this study.
Journal ArticleDOI
Quantitative determination of niraparib and olaparib tumor distribution by mass spectrometry imaging.
Lavinia Morosi,Cristina Matteo,Tommaso Ceruti,Silvia Giordano,Marianna Ponzo,Roberta Frapolli,Massimo Zucchetti,Enrico Davoli,Maurizio D'Incalci,Paolo Ubezio +9 more
TL;DR: These data confirm the validity of targeted mass spectrometry imaging for spatial quantitative measurement of drug distribution providing fundamental information for pharmacokinetic studies, drug discovery and the study of resistance mechanisms.