Cristina Vázquez-Carballo

TL;DR: These findings are the first to demonstrate the involvement of ferroptosis in rhabdomyolysis‐associated renal damage and its sensitivity to curcumin treatment andCurcumin may be a potential therapeutic approach for patients with this syndrome.

TL;DR: This review focuses on the key role of inflammation in the genesis and progression of DN, with a special interest in effector molecules and activated intracellular pathways leading to renal damage, as well as a comprehensive update of new therapeutic strategies targeting inflammation to prevent and/or retard renal injury.

TL;DR: In this article, the authors reviewed the role of TLRs in the initiation and development of acute kidney injury (AKI) as well as novel compounds targeting these molecules to diminish kidney injury associated to this pathological condition.

TL;DR: In this article, the authors review current knowledge on the protection mechanisms mediated by Nrf2 against kidney injury, novel therapeutic strategies to induce NRF2 activation, and the status of ongoing clinical trials targeting Nrf 2 in renal diseases.

TL;DR: This study identifies Nrf2 as a key molecule involved in protection against renal damage associated with hemolysis and opens novel therapeutic approaches to prevent renal damage in patients with severe hemolytic crisis.