D.J.G. Müller

TL;DR: The data on acrylamide levels in food including its formation and analytical methods, the determination of human consumption patterns, dietary intake of the general population, estimation of maximum intake levels and identification of groups of potentially high intakes are reviewed.

TL;DR: This report presents a review of risk characterisation, the final step in risk assessment of exposures to food chemicals, and describes good evaluation practice as an organisational process and the necessary condition under which risk Assessment of chemicals should be planned, performed, scrutinised and reported.

TL;DR: It is concluded that DNA from GMOs is equivalent to DNA from existing food organisms that has always been consumed with human diets and any risks associated with the consumption of DNA will remain, irrespective of its origin.

TL;DR: The margin of exposure (MOE) was the preferred approach because it is based on the available animal dose-response data, without extrapolation, and on human exposures, and there was consensus that it is difficult to interpret it in terms of health risk.

TL;DR: The present paper examines the particular difficulties presented by low levels of food-borne DNA-reactive genotoxic carcinogens, some of which may be difficult to eliminate completely from the diet, and proposes a structured approach for the evaluation of such compounds.