J
James W. Bridges
Researcher at University of Surrey
Publications - 152
Citations - 4901
James W. Bridges is an academic researcher from University of Surrey. The author has contributed to research in topics: Cytochrome & Metabolite. The author has an hindex of 38, co-authored 146 publications receiving 4713 citations. Previous affiliations of James W. Bridges include University of Mainz.
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Journal ArticleDOI
Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment.
David L. Eaton,Robert B. Daroff,Herman Autrup,James W. Bridges,Patricia A. Buffler,Lucio G. Costa,Joseph T. Coyle,Guy M. McKhann,William C. Mobley,Lynn Nadel,Diether Neubert,Rolf Schulte-Hermann,Peter S. Spencer +12 more
TL;DR: The results of this review demonstrate that the use of urinary 3,5,6-trichlorpyridinol (TCPy), a metabolite of chlorpyrifos as a biomarker of nonoccupational exposure is problematic and may overestimate non Occupational exposures to chlorparyifos by 10-to 20-fold because of the widespread presence of both TCPy and chlorp Pyrifos-methyl in the food supply.
Journal ArticleDOI
Possible effects of electromagnetic fields (EMF) on human health--opinion of the scientific committee on emerging and newly identified health risks (SCENIHR).
Anders Ahlbom,James W. Bridges,de Seze R,Lena Hillert,Jukka Juutilainen,Mats-Olof Mattsson,Georg Neubauer,Joachim Schüz,Myrtill Simkó,Bromen K +9 more
TL;DR: The previous opinion on "Possible effects of Electromagnetic Fields (EMF), Radio Frequency Fields (RF) and Microwave Radiation on human health" by the Scientific Committee on Toxicity, Ecotoxicity and the Environment from 2001 is updated.
Journal ArticleDOI
Risk assessment of substances that are both genotoxic and carcinogenic: Report of an International Conference organized by EFSA and WHO with support of ILSI Europe
Susan Barlow,Andrew G. Renwick,Juliane Kleiner,James W. Bridges,Leif Busk,E. Dybing,Lutz Edler,Gerhard Eisenbrand,Johanna Fink-Gremmels,A. Knaap,Rob Kroes,Djien Liem,D.J.G. Müller,S. Page,V. Rolland,Josef Rudolf Schlatter,Angelika Tritscher,W. Tueting,G. Würtzen +18 more
TL;DR: The margin of exposure (MOE) was the preferred approach because it is based on the available animal dose-response data, without extrapolation, and on human exposures, and there was consensus that it is difficult to interpret it in terms of health risk.
SCCP (Scientific Committee on Consumer Products) / SCHER (Scientific Committee on Health& Environment Risks) / SCENIHR (Scientific Committee on Emerging and Newly- Identified Health Risks) opinion on: Risk assessment methodologies and approaches for genotoxic and carcinogenic substances
Herman Autrup,James W. Bridges,Gisela H. Degen,Wolfgang Dekant,Helmut Greim,Hanke Wojciech,Inge Mangelsdorf,Thomas Platzek,Konrad Rydzyński,Tore Sanner,Anne Steenhout,Matti Viluksela,I. Anundi,A. Knaap,Ulrich Andrae,Peter Calow,Colin Janssen,Bo Jansson,Hannu Komulainen,Ole Ladefoged,Jan Linders,Marco Nuti,Jose Tarazona,Emanuela Testai,Marco Vighi +24 more
Journal ArticleDOI
The enzymic isolation of adult rat hepatocytes in a functional and viable state.
TL;DR: A modified method of collagenase/hyaluronidase digestion using a sequential removal and replacement of Ca 2+ and the omission of all perfusion steps has been evolved, thereby making the technique potentially viable for use with pieces of liver such as isolated human liver biopsy material.