J
Josef Rudolf Schlatter
Publications - 159
Citations - 7262
Josef Rudolf Schlatter is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 33, co-authored 112 publications receiving 5078 citations.
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Journal ArticleDOI
Structure-based thresholds of toxicological concern (TTC): guidance for application to substances present at low levels in the diet
Rob Kroes,Andrew G. Renwick,M Cheeseman,Juliane Kleiner,I Mangelsdorf,Aldert H. Piersma,Benoît Schilter,Josef Rudolf Schlatter,F van Schothorst,Josephus G. Vos,G. Würtzen +10 more
TL;DR: A recent reassessment of the use of TTCs, organized by ILSI Europe, has developed a decision tree which allows a systematic approach to the evaluation of low levels of diverse chemicals in food.
Journal ArticleDOI
Human exposure and internal dose assessments of acrylamide in food
E. Dybing,Peter B. Farmer,Melvin E. Andersen,Timothy R. Fennell,Sam P.D. Lalljie,D.J.G. Müller,Stephen S. Olin,Barbara J. Petersen,Josef Rudolf Schlatter,Gabriele Scholz,Joseph Scimeca,N. Slimani,Margareta Törnqvist,S. Tuijtelaars,Philippe Verger +14 more
TL;DR: The data on acrylamide levels in food including its formation and analytical methods, the determination of human consumption patterns, dietary intake of the general population, estimation of maximum intake levels and identification of groups of potentially high intakes are reviewed.
Journal ArticleDOI
Update: use of the benchmark dose approach in risk assessment
Anthony Hardy,Diane Benford,Thorhallur I. Halldorsson,Michael J. Jeger,Katrine Helle Knutsen,Simon J. More,Alicja Mortensen,Hanspeter Naegeli,Hubert Noteborn,Colin Ockleford,Antonia Ricci,Guido Rychen,Vittorio Silano,Roland Solecki,Dominique Turck,Marc Aerts,Laurent Bodin,Allen Davis,Lutz Edler,Ursula Gundert-Remy,Salomon Sand,Wout Slob,Bernard Bottex,José Cortiñas Abrahantes,Daniele Court Marques,George E.N. Kass,Josef Rudolf Schlatter +26 more
TL;DR: This updated guidance does not call for a general re‐evaluation of previous assessments where the NOAEL approach or the BMD approach as described in the 2009 SC guidance was used, in particular when the exposure is clearly smaller than the health‐based guidance value.
Journal ArticleDOI
Guidance on harmonised methodologies for human health, animal health and ecological risk assessment of combined exposure to multiple chemicals
Simon J. More,Vasileios Bampidis,Diane Benford,Susanne Hougaard Bennekou,Claude Bragard,Thorhallur I. Halldorsson,Antonio F Hernandez-Jerez,Konstantinos Koutsoumanis,Hanspeter Naegeli,Josef Rudolf Schlatter,Vittorio Silano,Søren Saxmose Nielsen,Dieter Schrenk,Dominique Turck,Maged Younes,Emilio Benfenati,Laurence Castle,Nina Cedergreen,Anthony Hardy,Ryszard Laskowski,Jean-Charles Leblanc,Andreas Kortenkamp,Ad M.J. Ragas,Leo Posthuma,Claus Svendsen,Roland Solecki,Emanuela Testai,Bruno Dujardin,George E.N. Kass,Paola Manini,Maryam Zare Jeddi,Jean Lou Cm Dorne,Christer Hogstrand +32 more
TL;DR: This Guidance document describes harmonised risk assessment methodologies for combined exposure to multiple chemicals for all relevant areas within EFSA's remit, i.e. human health, animal health and ecological areas.
Scientific Opinion of the Panel on Contaminants in the Food Chain
Jan Alexander,Diane Benford,Andrew Cockburn,Jean-Pierre Cravedi,Eugenia Dogliotti,Alessandro Di Domenico,María Luisa Fernández-Cruz,Peter Fürst,Johanna Fink-Gremmels,Lodovico Galli,Philippe Grandjean,Jadwiga Gzyl,Gerhard Heinemeyer,Antonio Mutti,Josef Rudolf Schlatter,Rolaf van Leeuwen,Carlos Van Peteghem,Philippe Verger +17 more
TL;DR: The Scientific Panel on Contaminants in the Food Chain (CONTAM Panel) concluded that because PTX-group toxins do not share the same mechanism of action as OAgroup toxins they should not be included in the regulatory limit for OA- group toxins.