D
D. James Nokes
Researcher at Wellcome Trust
Publications - 161
Citations - 7976
D. James Nokes is an academic researcher from Wellcome Trust. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 35, co-authored 133 publications receiving 6220 citations. Previous affiliations of D. James Nokes include University of Warwick & Kenya Medical Research Institute.
Papers
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Journal ArticleDOI
Efficiency of transplacental transfer of respiratory syncytial virus (RSV) specific antibodies among pregnant women in Kenya
Joyce U. Nyiro,Elizabeth A. Bukusi,Dufton Mwaengo,Amek Nyaguara,Bryan O. Nyawanda,Nancy A. Otieno,Godfrey Bigogo,Nickson Murunga,Jennifer R. Verani,Sandra S. Chaves,Hope Mwangudza,Calleb Odundo,James A. Berkley,D. James Nokes,Patrick K. Munywoki +14 more
TL;DR: In this article , the authors used a plaque reduction neutralization (PRN) assay to evaluate the efficiency of transplacental transfer of RSV-specific antibodies in a setting with a high burden of malaria and HIV.
Journal ArticleDOI
Does Viral Diversity Matter
TL;DR: The causes of epidemics of rotavirus, a major, global endemic virus, are investigated, with implications for childhood vaccination and the risk of future, widespread pandemics.
Posted ContentDOI
COVID-19 Transmission Dynamics Underlying Epidemic Waves in Kenya
Samuel Brand,Samuel Brand,Samuel Brand,John Ojal,John Ojal,Rabia Aziza,Rabia Aziza,Vincent Were,Emelda A. Okiro,Emelda A. Okiro,Ivy K. Kombe,Caroline Mburu,Morris Ogero,Ambrose Agweyu,Ambrose Agweyu,George M. Warimwe,George M. Warimwe,James Nyagwange,Henry K. Karanja,John N. Gitonga,Daisy Mugo,Sophie Uyoga,Ifedayo M. O. Adetifa,Ifedayo M. O. Adetifa,J. Anthony G. Scott,J. Anthony G. Scott,Edward Otieno,Nickson Murunga,Mark Otiende,Lynette Isabella Ochola-Oyier,Charles N. Agoti,George Githinji,Kadondi Kasera,Patrick Amoth,Mercy Mwangangi,Rashid Aman,Wangari Ng’ang’a,Benjamin Tsofa,Philip Bejon,Philip Bejon,Matthew James Keeling,Matthew James Keeling,D. James Nokes,D. James Nokes,D. James Nokes,Edwine Barasa,Edwine Barasa +46 more
TL;DR: In this paper, the authors used a mechanistic mathematical model to explain the first two distinct waves by differences in contact rates in high and low social-economic groups, and the third wave by the introduction of a new higher-transmissibility variant.
Journal ArticleDOI
Identifying the research, advocacy, policy and implementation needs for the prevention and management of respiratory syncytial virus lower respiratory tract infection in low- and middle-income countries
Xavier Carbonell-Estrany,Eric A. F. Simões,Louis Bont,Angela Gentile,Nusrat Homaira,Marcelo Comerlato Scotta,Renato T. Stein,Juan Pablo Torres,Jarju Sheikh,Shobha Broor,Najwa Khuri-Bulos,D. James Nokes,Patrick K. Munywoki,Quique Bassat,Arun Sharma,Sudha Basnet,Mary Chia Garba,Joanne De Jesus-Cornejo,Socorro Lupisan,Marta C. Nunes,Maduja V M Divarathna,John R. Fullarton,Barry Rodgers-Gray,Ian P. Keary,Mark Donald C Reñosa,Charl Verwey,David P. Moore,Faseeha Noordeen,Sushil K. Kabra,M. S. do Vale,Rolando Paternina-de la Ossa,Cristina Mariño,Josep Figueras-Aloy,Leonard R. Krilov,Eitan Naaman Berezin,Heather J. Zar,Krishna Chandra Paudel,Marco Aurélio Palazzi Sáfadi,Ghassan Dbaibo,Imane Jroundi,Runa Jha,Rukshan A M Rafeek,Rossiclei de Souza Pinheiro,Marianne Bracht,Rohitha Muthugala,Marcello Lanari,Federico Martinón-Torres,Ian Mitchell,Grace Irimu,Apsara Pandey,Anand Krishnan,Asuncion Mejias,Marcela Santos Correa da Costa,Shrijana Shrestha,Jeffrey M. Pernica,Felipe Cotrim de Carvalho,Rose Jalang`o,Hafsat Umar Ibrahim,Atana Uket Ewa,Gabriela Ensinck,Rolando Ulloa-Gutierrez,Alexandre Lopes Miralha,Maria Florencia Lucion,Md. Zakiul Hassan,Zubair Akhtar,Mohammad Abdul Aleem,Fahmida Chowdhury,Pablo Rojo,Charles J. Sande,Abednego Musau,K. Zaman,Luiza Helena,Falleiros Arlant,Prakash Ghimire,April Price,K. Subedi,Helena Brenes-Chacon,Doli Goswami,Mohammed M. Rahman,Mohammad Enayet Hossain,Mohammod Jobayer Chisti,Nestor E. Vain,Audrey Lim,Aaron Chiu,Jesse Papenburg,Maria Del Valle Juarez,Thamarasi Senaratne,Shiyamalee Arunasalam,Tor A. Strand,Adaeze C Ayuk,Olufemi Gboye Ogunrinde,L. Tavares,C. M. G. Garba,B. I. Garba,Jeanette Dawa,Michelle Gordon,Eric Osoro,Charles N. Agoti,Bryan O. Nyawanda,Mwanajuma Ngama,Collins Tabu,Joseph L. Mathew,Andrew Cornacchia,Ganesh Rai,Amita Jain,Mateus Giongo,Bosco Paes +106 more
TL;DR: In this paper , a survey-based study of RSV infection in young children disproportionately occurs in low and middle-income countries (LMICs), and seven key actions for improving RSV prevention and management in LMICs are proposed.
Journal ArticleDOI
Genomic epidemiology and evolutionary dynamics of respiratory syncytial virus group B in Kilifi, Kenya, 2015-17.
Everlyn Kamau,James R. Otieno,Nickson Murunga,John W. Oketch,Joyce M. Ngoi,Zaydah R. de Laurent,Anthony Mwema,Joyce U. Nyiro,Charles N. Agoti,Charles N. Agoti,D. James Nokes,D. James Nokes +11 more
TL;DR: An analysis of 295 RSV group B genomes from Kilifi, coastal Kenya, sampled from individuals seeking outpatient care in nine health facilities across a defined geographical area, identified a cluster of viruses that emerged in the 2016/17 epidemic, carrying distinct amino-acid signatures including a novel nonsynonymous change in antigenic site ∅ in the Fusion protein.