D
D. James Nokes
Researcher at Wellcome Trust
Publications - 161
Citations - 7976
D. James Nokes is an academic researcher from Wellcome Trust. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 35, co-authored 133 publications receiving 6220 citations. Previous affiliations of D. James Nokes include University of Warwick & Kenya Medical Research Institute.
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Mathematical model of the antibody response to hepatitis B vaccines: implications for reduced schedules.
TL;DR: A mathematical model of the generation of immune memory and antibody in response to hepatitis B vaccines is constructed and provides theoretical support for the hypothesis that a single vaccine dose can generate protective immune memory.
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Infectious disease and health systems modelling for local decision making to control neglected tropical diseases
T. Déirdre Hollingsworth,Ivor Langley,D. James Nokes,D. James Nokes,Eleanor E MacPherson,Gerry McGivern,Emily R. Adams,Moses J. Bockarie,Kevin Mortimer,Lisa J. Reimer,Bertie Squire,Stephen J. Torr,Graham F. Medley +12 more
TL;DR: It is argued that there will be a need to develop local quantitative expertise to support elimination efforts and that locally tailored quantitative analyses can help achieve sustainable and effective control of NTDs, but also underpin the development of local health care systems.
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Examining strain diversity and phylogeography in relation to an unusual epidemic pattern of respiratory syncytial virus (RSV) in a long-term refugee camp in Kenya
Charles N. Agoti,Lillian M. Mayieka,James R. Otieno,Jamal A. Ahmed,Barry S. Fields,Lilian W. Waiboci,Raymond Nyoka,Rachel B. Eidex,Nina Marano,Wagacha Burton,Joel M. Montgomery,Robert F. Breiman,Robert F. Breiman,D. James Nokes,D. James Nokes +14 more
TL;DR: RSV strain diversity in Dadaab was similar to contemporaneous diversity worldwide, suggested both between-epidemic persistence and new introductions, and was unrelated to the unusual epidemic pattern.
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Identifying infections with respiratory syncytial virus by using specific immunoglobulin G (IgG) and IgA enzyme-linked immunosorbent assays with oral-fluid samples
Emelda A. Okiro,Charles J. Sande,Martin Mutunga,Graham F. Medley,Patricia A. Cane,D. James Nokes,D. James Nokes +6 more
TL;DR: An indirect enzyme-linked immunosorbent assay for the detection of RSV-specific immunoglobulin G (IgG) and IgA is evaluated by using oral-fluid samples collected from individuals with RSV infections confirmed by an immunofluorescent antibody test, showing significant promise for the use of oral fluid alone in RSV infection surveillance.
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Complete Genome Sequences of Dengue Virus Type 2 Strains from Kilifi, Kenya
Everlyn Kamau,Charles N. Agoti,Joyce M. Ngoi,Zaydah R. de Laurent,John N. Gitonga,Matthew Cotten,My V. T. Phan,D. James Nokes,D. James Nokes,Eric Delwart,Eduard J. Sanders,Eduard J. Sanders,George M. Warimwe,George M. Warimwe +13 more
TL;DR: The authors reported dengue virus type 2 (DENV-2) sequence data from 10 clinical samples, including 5 complete genome sequences of the cosmopolitan genotype, obtained from febrile adults seeking outpatient care in coastal Kenya.