Dallas M. Hyde

TL;DR: The lung poses special challenges, some of which are outlined below and discussed in later sections: Heterogeneity of lung structure requires standardized preparation methods, and the practice of picking specific samples or sections often fails to account for regional heterogeneity, leading to biased conclusions with respect to the whole organ.

TL;DR: It is concluded that even mild asthma is associated with goblet cell hyperplasia and increased stored mucin in the airway epithelium, whereas moderate asthma isassociated with increased stored bronchial mucin and secreted mucin.

TL;DR: It is suggested that the vasa vasorum and circulating progenitor cells could be involved in vessel wall thickening in the setting of hypoxia-induced PH.

TL;DR: The new tools of quantitative morphology are described and it is shown how they can be used to design new experiments for lung research.

TL;DR: It is shown that OX40 ligand (OX40L) is a critical in vivo mediator of TSLP-mediated Th2 responses and presents a promising strategy for the treatment of allergic diseases associated with pathologic Th2 immune responses.