D
Dan Han
Researcher at Zhejiang University
Publications - 4
Citations - 1220
Dan Han is an academic researcher from Zhejiang University. The author has contributed to research in topics: Haematopoiesis & Gene silencing. The author has an hindex of 4, co-authored 4 publications receiving 956 citations.
Papers
More filters
Journal ArticleDOI
Circular RNA circMTO1 acts as the sponge of microRNA-9 to suppress hepatocellular carcinoma progression.
Dan Han,Jiangxue Li,Huamin Wang,Xiaoping Su,Jin Hou,Yan Gu,Cheng Qian,Yun Lin,Xiang Liu,Mingyan Huang,Nan Li,Weiping Zhou,Yizhi Yu,Xuetao Cao +13 more
TL;DR: In this article, the expression profile and function of circRNAs in human hepatocellular carcinoma (HCC) remain to be investigated, and the authors used a biotin-labeled circMTO1 probe to perform RNA in vivo precipitation in HCC cells.
Journal ArticleDOI
Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity
Kun Chen,Juan Liu,Shuxun Liu,Meng Xia,Xiaomin Zhang,Dan Han,Yingming Jiang,Chunmei Wang,Xuetao Cao,Xuetao Cao,Xuetao Cao +10 more
TL;DR: This study identifies STAT1 methylation on K525 catalyzed by the methyltransferase SETd2 as an essential signaling event for IFNα-dependent antiviral immunity and indicates potential of SETD2 in controlling viral infections.
Journal ArticleDOI
Adult Connective Tissue-Resident Mast Cells Originate from Late Erythro-Myeloid Progenitors
Zhiqing Li,Shuxun Liu,Junfang Xu,Xiang Zhang,Dan Han,Juan Liu,Meng Xia,Lin Yi,Qicong Shen,Sheng Xu,Linrong Lu,Xuetao Cao +11 more
TL;DR: Most connective tissue mast cells derive from fetal mast cells that arise from late erythro‐myeloid progenitors generated in the yolk sac at E8.5, showing embryonic origin shapes the heterogeneity of adult mast cells, with diverse functions in immunity and development.
Journal ArticleDOI
MicroRNA in vivo precipitation identifies miR-151-3p as a computational unpredictable miRNA to target Stat3 and inhibits innate IL-6 production
Xiang Liu,Xiaoping Su,Sheng Xu,Huamin Wang,Dan Han,Jiangxue Li,Mingyan Huang,Xuetao Cao,Xuetao Cao,Xuetao Cao +9 more
TL;DR: It was found that miR-151-3p inhibited LPS-induced IL-6 production by targeting Stat3, and this data further confirmed miRIP as an efficient method to identify unpredictable miRNAs and explore mi RNAs-mediated regulation in innate immunity and inflammation.