D
Daniel Choquet
Researcher at University of Bordeaux
Publications - 208
Citations - 20717
Daniel Choquet is an academic researcher from University of Bordeaux. The author has contributed to research in topics: AMPA receptor & Synaptic plasticity. The author has an hindex of 73, co-authored 200 publications receiving 18607 citations. Previous affiliations of Daniel Choquet include Centre national de la recherche scientifique & Necker-Enfants Malades Hospital.
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Extracellular Matrix Rigidity Causes Strengthening of Integrin–Cytoskeleton Linkages
TL;DR: The strength of integrin-cytoskeleton linkages is dependent on matrix rigidity and on its biochemical composition, and Matrix rigidity may, therefore, serve as a guidance cue in a process of mechanotaxis.
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The Interaction between Stargazin and PSD-95 Regulates AMPA Receptor Surface Trafficking
TL;DR: It is shown, using single quantum dot and FRAP imaging in live hippocampal neurons, that exchange of AMPAR by lateral diffusion between extrasynaptic and synaptic sites mostly depends on the interaction of Stargazin with PSD-95 and not upon the GluR2 AMPAR subunit C terminus.
Journal ArticleDOI
Regulation of AMPA receptor lateral movements
Aren J. Borgdorff,Daniel Choquet +1 more
TL;DR: It is suggested that calcium influx prevents AMPA receptors from diffusing, and that lateral receptor diffusion to and from synaptic sites acts in the rapid and controlled regulation of receptor numbers at synapses.
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Super-resolution imaging reveals that AMPA receptors inside synapses are dynamically organized in nanodomains regulated by PSD95.
Deepak T. Nair,Eric Hosy,Eric Hosy,Jennifer D. Petersen,Jennifer D. Petersen,Audrey Constals,Audrey Constals,Grégory Giannone,Grégory Giannone,Daniel Choquet,Daniel Choquet,Jean-Baptiste Sibarita,Jean-Baptiste Sibarita +12 more
TL;DR: The observation that AMPARs are highly concentrated in nanodomains, instead of diffusively distributed in the PSD as generally thought, has important consequences on the understanding of excitatory neurotransmission.
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Brain extracellular matrix affects AMPA receptor lateral mobility and short-term synaptic plasticity.
Renato Frischknecht,Martin Heine,Martin Heine,David Perrais,Constanze I. Seidenbecher,Daniel Choquet,Eckart D. Gundelfinger +6 more
TL;DR: The results suggest that the surface compartments formed by the ECM hinder lateral diffusion of AMPA receptors and may therefore modulate short-term synaptic plasticity.