D
Daniel Côté
Researcher at Laval University
Publications - 139
Citations - 8011
Daniel Côté is an academic researcher from Laval University. The author has contributed to research in topics: Microscopy & Raman spectroscopy. The author has an hindex of 38, co-authored 131 publications receiving 7069 citations. Previous affiliations of Daniel Côté include HEC Montréal & École Normale Supérieure.
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Journal ArticleDOI
Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy.
TL;DR: A sensitive technique for vibrational imaging of tissues by combining coherent anti-Stokes Raman scattering (CARS) with video-rate microscopy is developed and CARS imaging and spectroscopy of lipid-rich tissue structures in the skin of a live mouse is demonstrated, with unprecedented contrast at subcellular resolution.
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Direct measurement of local oxygen concentration in the bone marrow of live animals
Joel A. Spencer,Francesca Ferraro,Emmanuel Roussakis,Alyssa Klein,Juwell W. Wu,Judith Runnels,Walid Abbas Zaher,Luke J. Mortensen,Clemens Alt,Raphaël Turcotte,Rushdia Z. Yusuf,Daniel Côté,Sergei A. Vinogradov,David T. Scadden,Charles P. Lin +14 more
TL;DR: These pO2 values change markedly after radiation and chemotherapy, pointing to the role of stress in altering the stem cell metabolic microenvironment.
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Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche
Cristina Lo Celso,Heather E. Fleming,Juwell W. Wu,Cher X. Zhao,Sam Miake-Lye,Joji Fujisaki,Daniel Côté,Daniel Côté,David W. Rowe,Charles P. Lin,David T. Scadden +10 more
TL;DR: The relationship of haematopoietic stem and progenitor cells to blood vessels, osteoblasts and endosteal surface as they home and engraft in irradiated and c-Kit-receptor-deficient recipient mice is examined.
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In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment
Dorothy A. Sipkins,Xunbin Wei,Juwell W. Wu,Judith Runnels,Daniel Côté,Terry K. Means,Andrew D. Luster,David T. Scadden,Charles P. Lin +8 more
TL;DR: It is shown that murine bone marrow contains unique anatomic regions defined by specialized endothelium, which appears to delineate a microenvironment with unique physiology that can be exploited by circulating malignant cells.
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In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche
Joji Fujisaki,Juwell W. Wu,Juwell W. Wu,Alicia L. Carlson,Lev Silberstein,Prabhakar Putheti,Rafael A. Larocca,Wenda Gao,Toshiki I. Saito,Toshiki I. Saito,Cristina Lo Celso,Hitoshi Tsuyuzaki,Tatsuyuki Sato,Daniel Côté,Megan Sykes,Megan Sykes,Terry B. Strom,David T. Scadden,Charles P. Lin +18 more
TL;DR: In this article, the bone marrow haematopoietic stem cell (HSC) niche is identified as an immune privileged site, where regulatory T cells are necessary for allo-HSPC persistence.