E
Eric O. Potma
Researcher at University of California, Irvine
Publications - 205
Citations - 8981
Eric O. Potma is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Microscopy & Raman scattering. The author has an hindex of 45, co-authored 188 publications receiving 7889 citations. Previous affiliations of Eric O. Potma include Harvard University & University of California.
Papers
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Journal ArticleDOI
Killing activity of neutrophils is mediated through activation of proteases by K + flux
Emer P. Reeves,Hui Lu,Hugues Lortat Jacobs,Carlo Messina,Steve Bolsover,Giorgio Gabella,Eric O. Potma,Alice Warley,Jürgen Roes,Anthony W. Segal +9 more
TL;DR: It is shown that mice made deficient in neutrophil-granule proteases but normal in respect of superoxide production and iodinating capacity, are unable to resist staphylococcal and candidal infections.
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Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy.
TL;DR: A sensitive technique for vibrational imaging of tissues by combining coherent anti-Stokes Raman scattering (CARS) with video-rate microscopy is developed and CARS imaging and spectroscopy of lipid-rich tissue structures in the skin of a live mouse is demonstrated, with unprecedented contrast at subcellular resolution.
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Heterodyne coherent anti-Stokes Raman scattering (CARS) imaging.
TL;DR: It is shown that heterodyne CARS microscopy permits the detection of weak vibrational resonances that are otherwise overshadowed by the strong interference of the nonresonant background.
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Seeing a single molecule vibrate through time-resolved coherent anti-Stokes Raman scattering
Steven Yampolsky,Dmitry A. Fishman,Shirshendu Dey,Eero Hulkko,Eero Hulkko,Mayukh Banik,Eric O. Potma,V. A. Apkarian +7 more
TL;DR: In this article, the vibrations of a single molecule are observed by employing time-resolved coherent anti-Stokes Raman scattering and a gold nano-antenna is used to enhance the signal from the molecule.
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Nonperturbative Chemical Imaging of Organelle Transport in Living Cells with Coherent Anti-Stokes Raman Scattering Microscopy
TL;DR: Simultaneous imaging of LDs and mitochondria with CARS and two-photon fluorescence microscopy clearly showed that interactions between the two organelles could be facilitated by high LD motility, demonstrating CARS microscopy as a powerful noninvasive imaging tool for studying dynamic processes in living cells.