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Helen Fifer

Researcher at Public Health England

Publications -  74
Citations -  1946

Helen Fifer is an academic researcher from Public Health England. The author has contributed to research in topics: Medicine & Neisseria gonorrhoeae. The author has an hindex of 16, co-authored 53 publications receiving 1349 citations.

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Failure of Dual Antimicrobial Therapy in Treatment of Gonorrhea

TL;DR: The clinical failure of ceftriaxone and azithromycin in a patient with gonorrhea is described.
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Gonorrhoea treatment failure caused by a Neisseria gonorrhoeae strain with combined ceftriaxone and high-level azithromycin resistance, England, February 2018

TL;DR: A heterosexual male was diagnosed with gonorrhoea in the United Kingdom following sexual intercourse with a locally resident female in Thailand and failed treatment with ceftriaxone plus doxycycline and subsequently spectinomycin, resulting in resistance arose from two mechanisms combining for the first time in a genetic background similar to a commonly circulating strain.
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2018 UK national guideline for the management of infection with Neisseria gonorrhoeae

TL;DR: Changes since 2011 guideline • First line empirical treatment is now monotherapy with ceftriaxone 1 g intramuscularly • If antimicrobial susceptibility test results from all sites of infection are available prior to treatment and the isolate is sensitive to ciprofloxacin, then this should be used for treatment in preference to ceftRIaxone