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Daniel J. Lenihan

Researcher at Vanderbilt University Medical Center

Publications -  166
Citations -  9052

Daniel J. Lenihan is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Heart failure & Cancer. The author has an hindex of 32, co-authored 140 publications receiving 6193 citations. Previous affiliations of Daniel J. Lenihan include Vanderbilt University.

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Cardio-oncology: a tremendous opportunity to improve patient care

TL;DR: For over 20 years, Daniel J Lenihan has been active in clinical research in heart failure, and the main focuses of his work have included hemodynamic assessments, angiogenic growth factor response, novel cardiac biomarkers and optimal methods to prevent or detect heart failure at the earliest stage possible in patients undergoing treatment for cancer.
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Evaluation of cardiac function in symptomatic heart failure patients in a single infusion, phase 1, dose escalation study of glial growth factor 2

TL;DR: Echocardiographic findings in a first-in-man, double-blind, placebo controlled, escalating single dose study of GGF2 improve left ventricular function in animal models of cardiac injury are reported.
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Cardiotoxicity during cancer treatment causes more regional than global dysfunction: the prefect study

TL;DR: The PREFECT study evaluates fast-SENC CMR (fSENC) as a measure of cardiotoxicity and calculates left ventricular ejection fraction and global strain to monitor cardiot toxicity.
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Infiltrative cardiomyopathy and pericardial disease

TL;DR: Three potential infiltrative conditions of the myocardium with associated cardiomyopathies that are encountered in cancer patients are illustrated: cardiac amyloid, iron overload, and lymphomatous infiltration.
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Heart failure with preserved left ventricular function: diagnostic and therapeutic challenges in patients with diastolic heart failure.

TL;DR: A careful review of the diagnostic challenges of HFpEF or diastolic heart failure, current recommendations for management and a glimpse of upcoming research are presented.