D
Daniel K. Bricker
Researcher at University of Utah
Publications - 7
Citations - 1046
Daniel K. Bricker is an academic researcher from University of Utah. The author has contributed to research in topics: Pyruvate decarboxylation & Pyruvate carboxylase. The author has an hindex of 6, co-authored 7 publications receiving 845 citations. Previous affiliations of Daniel K. Bricker include University of Nevada, Las Vegas & Children's Hospital of Philadelphia.
Papers
More filters
Journal ArticleDOI
A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.
Daniel K. Bricker,Eric B. Taylor,John C. Schell,Thomas Orsak,Audrey Boutron,Yu-Chan Chen,James E. Cox,Caleb M. Cardon,Jonathan G. Van Vranken,Noah Dephoure,Claire Redin,Sihem Boudina,Steven P. Gygi,Michèle Brivet,Carl S. Thummel,Jared Rutter +15 more
TL;DR: Human genetic studies of three families with children suffering from lactic acidosis and hyperpyruvatemia revealed a causal locus that mapped to MPC1, changing single amino acids that are conserved throughout eukaryotes, demonstrating that Mpc1 and Mpc2 form an essential part of the mitochondrial pyruvate carrier.
Journal ArticleDOI
The LYR Factors SDHAF1 and SDHAF3 Mediate Maturation of the Iron-Sulfur Subunit of Succinate Dehydrogenase
Un Na,Wendou Yu,James E. Cox,Daniel K. Bricker,Knut Brockmann,Jared Rutter,Carl S. Thummel,Dennis R. Winge +7 more
TL;DR: Yeast studies revealed that Sdh6 and Sdh7 act together to promote Sdh2 maturation by binding to a Sdh1/Sdh2 intermediate, protecting it from the deleterious effects of oxidants.
Journal ArticleDOI
A Novel Ecdysone Receptor Mediates Steroid-Regulated Developmental Events during the Mid-Third Instar of Drosophila
Benjamin F. B. Costantino,Daniel K. Bricker,Kelly Alexandre,Kate Shen,John R. Merriam,Christophe Antoniewski,Jenna Callender,Vincent C. Henrich,Asaf Presente,Andrew J. Andres +9 more
TL;DR: It is shown that the coordinated expression of the glue genes midway through the third instar is mediated by 20E acting to induce genes of the Broad Complex (BRC) through a receptor that is not an EcR/USP heterodimer.
Journal ArticleDOI
SDHAF4 promotes mitochondrial succinate dehydrogenase activity and prevents neurodegeneration.
Jonathan G. Van Vranken,Daniel K. Bricker,Noah Dephoure,Steven P. Gygi,James E. Cox,Carl S. Thummel,Jared Rutter +6 more
TL;DR: An evolutionarily conserved SDH assembly factor designated Sdh8/SDHAF4 is characterized, providing insights into the mechanisms by which SDH is assembled and raising the possibility that some forms of neuromuscular disease may be associated with mutations that affect this SDHAssembly factor.
Journal ArticleDOI
Identifying Host Factors Associated with DNA Replicated During Virus Infection.
Emigdio D. Reyes,Emigdio D. Reyes,Katarzyna Kulej,Katarzyna Kulej,Neha J. Pancholi,Neha J. Pancholi,Lisa N. Akhtar,Daphne C. Avgousti,Daphne C. Avgousti,Eui Tae Kim,Daniel K. Bricker,Daniel K. Bricker,Lynn A. Spruce,Sarah A. Koniski,Steven H. Seeholzer,Stuart N. Isaacs,Benjamin A. Garcia,Matthew D. Weitzman,Matthew D. Weitzman +18 more
TL;DR: This work uncovered host factors deactivated by early viral proteins, and identified a subgroup of nucleolar proteins that aid virus replication that is associated with viral genomes during infection with adenovirus, herpes simplex virus and vaccinia virus.