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Daniel L. Segal
Researcher at University of Colorado Colorado Springs
Publications - 258
Citations - 16608
Daniel L. Segal is an academic researcher from University of Colorado Colorado Springs. The author has contributed to research in topics: Personality disorders & Personality. The author has an hindex of 47, co-authored 245 publications receiving 15372 citations. Previous affiliations of Daniel L. Segal include Nova Southeastern University & Boston College.
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Journal ArticleDOI
Tryptophan-galactosylamine conjugates inhibit and disaggregate amyloid fibrils of Aβ42 and hIAPP peptides while reducing their toxicity
Ashim Paul,Moran Frenkel-Pinter,Daniela Escobar Alvarez,Giulia Milordini,Ehud Gazit,Elsa Zacco,Elsa Zacco,Daniel L. Segal +7 more
TL;DR: Paul et al. provide a rational design strategy to develop dual inhibitors, in the form of tryptophan-galactosylamine conjugates, against amyloid formation and aggregation of Aβ42 and hIAPP peptides, which potentially could serve as scaffolds for development of Alzheimer’s disease therapeutics.
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Differential effects of putative N-glycosylation sites in human Tau on Alzheimer's disease-related neurodegeneration
Yelena Losev,Moran Frenkel-Pinter,Malak Abu-Hussien,Guru KrishnaKumar Viswanathan,Donna Elyashiv-Revivo,Rana Geries,Isam Khalaila,Ehud Gazit,Daniel L. Segal +8 more
TL;DR: High-performance liquid chromatography and mass spectrometry analysis indicated that both N359 and N410 were N- glycosylated in wild-type (WT) human Tau ( h Tau) expressed in human SH-SY5Y cells.
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Genetics for improving biological control agents: the case of entomopathogenic nematodes
Daniel L. Segal,Itamar Glazer +1 more
TL;DR: The success in genetic transformation of EPN opens the way for generating transgenic nematodes carrying genes conferring resistance to various environmental extremes.
Journal Article
Phenotypic and Genetic Analysis of a Mutant of Heterorhabditis bacteriophora Strain HP88.
TL;DR: Backcross with the original population was successful only between mutant hermaphrodites and wild type males; 50-100 percent of the progeny of this cross maintained thedumpy phenotype, indicating that the ratio between self- and external fertilization of the eggs is > 1 and that the dumpy mutation is recessive.
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Levels of Knowledge About Suicide Facts and Myths Among Younger and Older Adults
TL;DR: Despite the fact that older adults have the highest suicide rate of any age group, little is known about the kind of information older adults possess about suicide facts as discussed by the authors. But, they do possess a higher suicide rate than younger adults.