Daniel R. Abánades

TL;DR: This study demonstrates that differences in the parasite challenge result in changes in the evolution of some of the parameters associated with the degree of the infection in the BALB/c model: level of anti‐Leishmania antibodies, up‐regulation of spleen arginase activity, balance between IFN‐γ and IL‐10, extent of lymphoid follicle depletion in the splenic white pulp and ineffective development of hepatic granulomas.

TL;DR: The data argue that HO-1 has a critical role in the L. chagasi infection and is strongly associated with the inflammatory imbalance during VL, which could serve as an adjunctive therapeutic approach.

TL;DR: A procedure for immunological detection of AX-protein adducts with antibodies recognizing the lateral chain of the AX molecule is reported, providing novel tools and insight for the study of protein haptenation and the mechanisms involved in AX-elicited allergic reactions.

TL;DR: The data presented indicate that the engineered NQC-AmpB nanoparticles could potentially be used as an alternative therapy to treat leishmaniasis, mainly due its low toxicity to mammals’ cells.

TL;DR: A new family of fluorescent synthetic molecular probes for nitric oxide sensing based on ortho-hydroxyamino-triarylpyrylium salts is presented.