Daniel Roxbury

TL;DR: An engineered carbon-nanotube-based sensor capable of real-time optical quantification of hybridization events of microRNA and other oligonucleotides is reported, which allows for detection via single-molecule sensor elements and for multiplexing by using multiple nanotube chiralities.

TL;DR: A targeted drug delivery system that is accurately and quantitatively predicted to self-assemble into nanoparticles based on the molecular structures of precursor molecules, which are the drugs themselves.

TL;DR: It is reported that DNA forms ordered structures on SWCNTs that are strongly DNA sequence andSWCNT dependent, and Experimental measurements show that (TAT)(4) selectively disperses smaller diameter SWC NTs more efficiently than (T)(12), establishing a relationship between recognition motifs and binding strength.

TL;DR: This work presents a wide-field hyperspectral approach to spatially delineate and spectroscopically measure single nanotube fluorescence in living systems and expects that this approach will facilitate multiplexed nanotubes imaging in biomedical applications while enabling deep-tissue optical penetration, and single-molecule resolution in vivo.

TL;DR: Fluorescence studies support the finding that the DNA sequence that recognizes the (6,5)-CNT forms a more stable hybrid than its close relatives.