D
Daniela Perani
Researcher at Vita-Salute San Raffaele University
Publications - 379
Citations - 32933
Daniela Perani is an academic researcher from Vita-Salute San Raffaele University. The author has contributed to research in topics: Dementia & Cognition. The author has an hindex of 88, co-authored 350 publications receiving 30491 citations. Previous affiliations of Daniela Perani include University of Milan & University of Milano-Bicocca.
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Journal ArticleDOI
Functional Basis of Memory Impairment in Multiple Sclerosis: A [18F]FDG PET Study
Eraldo Paulesu,Daniela Perani,Ferruccio Fazio,Giancarlo Comi,Carlo Pozzilli,Vittorio Martinelli,Massimo Filippi,Valentino Bettinardi,G. Sirabian,D. Passafiume,A. Anzini,Gian Luigi Lenzi,Nicola Canal,Cesare Fieschi +13 more
TL;DR: The findings indicate that hypometabolism of thalamic and deep cortical gray structures of the temporal lobe is associated with episodic memory dysfunction in MS and pathological performance on tests designed to assess frontal functions was associated with widespread reduction of glucose metabolism.
Journal ArticleDOI
Impairment of neocortical metabolism predicts progression in Alzheimer's disease
Karl Herholz,Agneta Nordberg,Eric Salmon,Daniela Perani,Josef Kessler,R. Mielke,M. Halber,Vesna Jelic,Ove Almkvist,Fabienne Collette,Margherita Alberoni,A. Kennedy,Steen G. Hasselbalch,F. Fazio,W.-D. Heiss +14 more
TL;DR: A prospective longitudinal analysis showed a significant association between initial metabolic impairment and subsequent clinical deterioration in patients with mild cognitive deficits, and the risk of deterioration was up to 4.7 times higher if the metabolism was severely impaired than with mild or absent metabolic impairment.
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Metabolic Impairment in Human Amnesia: A PET Study of Memory Networks
Ferruccio Fazio,Daniela Perani,Maria Carla Gilardi,Fabio Colombo,Stefano F. Cappa,Giuseppe Vallar,Valentino Bettinardi,Eraldo Paulesu,Margherita Alberoni,S. Bressi,Massimo Franceschi,Gian Luigi Lenzi +11 more
TL;DR: In vivo evidence for the role of a functional network as a basis of human memory is found in patients with “pure” amnesia, finding a significant bilateral reduction in metabolism in a number of interconnected cerebral regions.
Journal ArticleDOI
Basal ganglia and thalamo-cortical hypermetabolism in patients with spasmodic torticollis
Giuseppe Galardi,Daniela Perani,F. Grassi,S Bressi,Stefano Amadio,M. Antoni,Giancarlo Comi,Nicola Canal,F. Fazio +8 more
TL;DR: The hypothesis that a dysfunction of a subcortical‐Cortical motor network may play a role in the pathogenesis of focal dystonia is supported, in agreement with the experimental dystonias models.
Journal ArticleDOI
Visuomotor Transformations for Reaching to Memorized Targets: A PET Study
Francesco Lacquaniti,Francesco Lacquaniti,Daniela Perani,Emmanuel Guigon,Valentino Bettinardi,Marco Carrozzo,F. Grassi,Yves Rossetti,F. Fazio +8 more
TL;DR: The activation of two partially distinct cerebral networks in these two motor tasks reflects the different nature of signal processing involved and appears characteristic of a network for visuospatial working memory.