D
David A.H. Whiteman
Researcher at Shire plc
Publications - 39
Citations - 1317
David A.H. Whiteman is an academic researcher from Shire plc. The author has contributed to research in topics: Hunter syndrome & Mucopolysaccharidosis type II. The author has an hindex of 21, co-authored 32 publications receiving 1185 citations. Previous affiliations of David A.H. Whiteman include Boston Children's Hospital & Wake Forest University.
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Journal ArticleDOI
Long-term, open-labeled extension study of idursulfase in the treatment of Hunter syndrome
Joseph Muenzer,Michael Beck,Christine M. Eng,Roberto Giugliani,Paul Harmatz,Rick A. Martin,Uma Ramaswami,Ashok Vellodi,James E. Wraith,Maureen Cleary,Muge Gucsavas-Calikoglu,Ana Cristina Puga,Marwan Shinawi,Birgit Ulbrich,Suresh Vijayaraghavan,Susanne Wendt,Anne Marie Conway,Alexandra Rossi,David A.H. Whiteman,Alan Kimura +19 more
TL;DR: In this paper, the safety and effectiveness of long-term enzyme replacement therapy with idursulfase (recombinant human iduronate-2-sulfatase) in patients with Hunter syndrome was evaluated.
Journal ArticleDOI
Cerebrovascular complications in Ehlers-Danlos syndrome type IV
TL;DR: 19 individuals with EDS type IV were identified with cerebrovascular complications, which included intracranial aneurysms with secondary hemorrhage, spontaneous carotidcavernous sinus fistula, and cervical artery dissection, which are an important potential cause of stroke in young people.
Journal ArticleDOI
The human ribosomal RNA genes: structure and organization of the complete repeating unit
J. E. Sylvester,David A.H. Whiteman,R. Podolsky,Judith M. Pozsgay,J. Respess,R. D. Schmickel +5 more
TL;DR: The analysis of spacer DNA by molecular cloning and its organization in the genome by Southern transfer analysis reveal both length and sequence variation of the spacer.
Journal ArticleDOI
Defects of mitochondrial β-oxidation: a growing group of disorders
TL;DR: Clinical symptoms, diagnostic testing, and issues of newborn screening for this important group of disorders affecting β-oxidation in skeletal muscle and other tissues have been discussed.
Journal ArticleDOI
Optic nerve coloboma associated with renal disease.
R. Grey Weaver,L. Frank Cashwell,William B. Lorentz,David A.H. Whiteman,Kim R. Geisinger,M. R. Ball,John M. Optiz,James F. Reynolds +7 more
TL;DR: This second familial occurrence suggests that the association of optic nerve coloboma and renal disease is a newly recognized syndrome.