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David A. Kass
Researcher at Johns Hopkins University School of Medicine
Publications - 605
Citations - 63963
David A. Kass is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Heart failure & Cardiac resynchronization therapy. The author has an hindex of 127, co-authored 580 publications receiving 58747 citations. Previous affiliations of David A. Kass include University of Pittsburgh & Johns Hopkins University.
Papers
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Journal ArticleDOI
Evaluation of contractile state by maximal ventricular power divided by the square of end-diastolic volume.
David A. Kass,Rafael Beyar +1 more
TL;DR: PWRU, divided by EDV2 provides a measure of contractile function that is little influenced by loading conditions and has potential for noninvasive clinical use.
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Mechanical Dyssynchrony in Dilated Cardiomyopathy With Intraventricular Conduction Delay as Depicted by 3D Tagged Magnetic Resonance Imaging
Cecilia W. Curry,Gregory S. Nelson,Bradley T. Wyman,Jerome Declerck,Maurice Talbot,Ronald D. Berger,Elliot R. McVeigh,David A. Kass +7 more
TL;DR: The extent of mechanical dyssynchrony in patients with dilated cardiomyopathy and intraventricular conduction delays is demonstrated and it is shown that pacing can restore synchronization and, thereby, improve function.
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Nitroxyl (HNO) a Novel Approach for the Acute Treatment of Heart Failure
Hani N. Sabbah,Carlo G. Tocchetti,Mengjun Wang,Samantapudi Daya,Ramesh C. Gupta,Richard S. Tunin,Reza Mazhari,Eiki Takimoto,Nazareno Paolocci,Douglas Cowart,Wilson S. Colucci,David A. Kass +11 more
TL;DR: These data show the functional efficacy of a novel, stable, pure HNO donor to enhance myocardial function and present first-in-man evidence for its potential usefulness in HF.
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Cardioprotective effect of beta-3 adrenergic receptor agonism: role of neuronal nitric oxide synthase.
Xiaolin Niu,Xiaolin Niu,Vabren L. Watts,Oscar H. Cingolani,Vidhya Sivakumaran,Jordan S Leyton-Mange,Carla LaShannon Ellis,Karen L. Miller,Konrad Vandegaer,Djahida Bedja,Kathleen L. Gabrielson,Nazareno Paolocci,David A. Kass,Lili A. Barouch +13 more
TL;DR: In this paper, the effect of β3-adrenergic receptor (AR) activation and downstream signaling of nitric oxide synthase (NOS) isoforms on the heart from failure and hypertrophy induced by pressure overload was investigated.
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Advanced glycation end product cross-linking: pathophysiologic role and therapeutic target in cardiovascular disease.
Susan J. Zieman,David A. Kass +1 more
TL;DR: New pharmacologic agents that prevent AGE, break cross-links, or block AGE receptors reduce vascular and myocardial stiffness, inhibit atherosclerotic plaque formation, and improve endothelial function, and thus, heart failure.