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David A. Kass
Researcher at Johns Hopkins University School of Medicine
Publications - 605
Citations - 63963
David A. Kass is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Heart failure & Cardiac resynchronization therapy. The author has an hindex of 127, co-authored 580 publications receiving 58747 citations. Previous affiliations of David A. Kass include University of Pittsburgh & Johns Hopkins University.
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Journal ArticleDOI
Transient circadian internal desynchronization after light-dark phase shift in monkeys
TL;DR: The results suggest that the circadian timing system in S. sciureus may consist of several spontaneously oscillating units which can become transiently uncoupled during pertubations of environmental time cues.
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RGS2 Is a Primary Terminator of β2-Adrenergic Receptor-Mediated Gi Signaling
Khalid Chakir,Weizhong Zhu,Sharon Tsang,Anthony Yiu-Ho Woo,Anthony Yiu-Ho Woo,Dongmei Yang,Xianhua Wang,Xianhua Wang,Xiaokun Zeng,Man Hee Rhee,Ulrike Mende,Norimichi Koitabashi,Eiki Takimoto,Kendall J. Blumer,Edward G. Lakatta,David A. Kass,Rui-Ping Xiao,Rui-Ping Xiao +17 more
TL;DR: RGS2 is defined as a novel negative regulator of the β(2)AR-G(i) signaling but also provides a potential novel target for the treatment of chronic heart failure.
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Protein S-Nitrosylation Controls Glycogen Synthase Kinase 3β Function Independent of Its Phosphorylation State.
Shengbing Wang,Vidya Venkatraman,Erin L. Crowgey,Ting Liu,Zongming Fu,Ronald J. Holewinski,Mark J. Ranek,David A. Kass,Brian O'Rourke,Jennifer E. Van Eyk +9 more
TL;DR: The results indicate that SNO has a differential effect on the location and activity of GSK-3&bgr; in the cytoplasm versus the nucleus and could contribute to the pathobiology of heart failure and sudden cardiac death.
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Large Particle Fluorescence-Activated Cell Sorting Enables High-Quality Single-Cell RNA Sequencing and Functional Analysis of Adult Cardiomyocytes.
Suraj Kannan,Matthew Miyamoto,Brian M. Lin,Renjun Zhu,Sean Murphy,David A. Kass,Peter Andersen,Chulan Kwon +7 more
TL;DR: This study demonstrates that LP-FACS enables rapid, high-throughput isolation of cardiomyocytes through use of large particle FACS, designed for the isolation of large objects, including worm/fly embryos and cell clusters.
Journal ArticleDOI
Tetrahydrobiopterin Protects Against Hypertrophic Heart Disease Independent of Myocardial Nitric Oxide Synthase Coupling.
Toru Hashimoto,Vidhya Sivakumaran,Ricardo Carnicer,Guangshuo Zhu,Virginia S. Hahn,Djahida Bedja,Alice Recalde,Drew Duglan,Keith M. Channon,Barbara Casadei,David A. Kass +10 more
TL;DR: BH4 protection against adverse remodeling in hypertrophic cardiac disease is not driven by its prevention of myocardial nitric oxide synthase uncoupling, as presumed previously, and benefits from exogenous BH4 are mediated by a protective effect coupled to suppression of inflammatory pathways and myocardian macrophage infiltration.