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David A. Meekins
Researcher at Kansas State University
Publications - 44
Citations - 1296
David A. Meekins is an academic researcher from Kansas State University. The author has contributed to research in topics: Biology & Glucan. The author has an hindex of 14, co-authored 35 publications receiving 735 citations. Previous affiliations of David A. Meekins include University of Kentucky.
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Journal ArticleDOI
SARS-CoV-2 infection, disease and transmission in domestic cats.
Natasha N. Gaudreault,Jessie D. Trujillo,Mariano Carossino,David A. Meekins,Igor Morozov,Daniel W. Madden,Sabarish V. Indran,Dashzeveg Bold,Velmurugan Balaraman,Taeyong Kwon,Bianca Libanori Artiaga,Konner Cool,Adolfo García-Sastre,Wenjun Ma,William C. Wilson,Jamie Henningson,Udeni B. R. Balasuriya,Juergen A. Richt +17 more
TL;DR: The results of this study are critical for understanding the clinical course of SARS-CoV-2 in a naturally susceptible host species, and for risk assessment.
Journal ArticleDOI
The Phosphoglucan Phosphatase Like Sex Four2 Dephosphorylates Starch at the C3-Position in Arabidopsis
Diana Santelia,Oliver Kötting,David Seung,Mario Schubert,Matthias Thalmann,Sylvain Bischof,David A. Meekins,Andy Lutz,Nicola J. Patron,Matthew S. Gentry,Frédéric H.-T. Allain,Samuel C. Zeeman +11 more
TL;DR: This work identifies an enzyme, named Like Sex Four2 (LSF2), that hydrolyzes the phosphate group from the C3-position of glucosyl residues of starch, a novel enzyme involved in starch metabolism in Arabidopsis chloroplasts.
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Serpins in arthropod biology
TL;DR: The field of serpins in arthropod biology is reviewed, providing an overview of current knowledge and topics of interest and the known structures of arthropody represent the serpin inhibitory mechanism and provide a detailed overview of the process.
Posted ContentDOI
The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera
Raveen Rathnasinghe,Sonia Jangra,Anastasija Cupic,Carles Martínez-Romero,Lubbertus C. F. Mulder,Thomas Kehrer,Soner Yildiz,Angela Choi,Ignacio Mena,Jana De Vrieze,Sadaf Aslam,Daniel Stadlbauer,David A. Meekins,Chester McDowell,Velmurugan Balaraman,Juergen A. Richt,Bruno G. De Geest,Lisa Miorin,Florian Krammer,Viviana Simon,Adolfo García-Sastre,Michael Schotsaert +21 more
TL;DR: In this paper, a mouse-adapted SARS-CoV-2 was serial passed through a clinical virus isolate in the lungs of mice and then used low doses of this virus in mouse models for advanced age, diabetes and obesity.
Journal ArticleDOI
Susceptibility of swine cells and domestic pigs to SARS-CoV-2
David A. Meekins,Igor Morozov,Jessie D. Trujillo,Natasha N. Gaudreault,Dashzeveg Bold,Mariano Carossino,Bianca Libanori Artiaga,Sabarish V. Indran,Taeyong Kwon,Velmurugan Balaraman,Daniel W. Madden,Heinz Feldmann,Jamie Henningson,Wenjun Ma,Wenjun Ma,Udeni B. R. Balasuriya,Juergen A. Richt +16 more
TL;DR: It is indicated that although different porcine cell lines are permissive to SARS-CoV-2, five-week old pigs are not susceptible to infection via oral/intranasal/intratracheal challenge and are not a suitable pre-clinical animal model to study Sars-Cov-2 pathogenesis or efficacy of respective vaccines or therapeutics.