V
Velmurugan Balaraman
Researcher at Kansas State University
Publications - 32
Citations - 1032
Velmurugan Balaraman is an academic researcher from Kansas State University. The author has contributed to research in topics: Biology & Virus. The author has an hindex of 12, co-authored 26 publications receiving 551 citations. Previous affiliations of Velmurugan Balaraman include University of Notre Dame & University of Missouri.
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Journal ArticleDOI
SARS-CoV-2 infection, disease and transmission in domestic cats.
Natasha N. Gaudreault,Jessie D. Trujillo,Mariano Carossino,David A. Meekins,Igor Morozov,Daniel W. Madden,Sabarish V. Indran,Dashzeveg Bold,Velmurugan Balaraman,Taeyong Kwon,Bianca Libanori Artiaga,Konner Cool,Adolfo García-Sastre,Wenjun Ma,William C. Wilson,Jamie Henningson,Udeni B. R. Balasuriya,Juergen A. Richt +17 more
TL;DR: The results of this study are critical for understanding the clinical course of SARS-CoV-2 in a naturally susceptible host species, and for risk assessment.
Journal ArticleDOI
Vulnerability of primitive human placental trophoblast to Zika virus.
Megan A. Sheridan,Dinar Yunusov,Dinar Yunusov,Dinar Yunusov,Velmurugan Balaraman,Andrei P. Alexenko,Shinichiro Yabe,Sergio Verjovski-Almeida,Sergio Verjovski-Almeida,Danny J. Schust,Alexander W. E. Franz,Yoel Sadovsky,Toshihiko Ezashi,R. Michael Roberts +13 more
TL;DR: It is concluded that the human fetus may be most vulnerable to ZIKV very early in pregnancy and that the African strain may threaten a pregnancy more strongly than previously believed.
Posted ContentDOI
The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera
Raveen Rathnasinghe,Sonia Jangra,Anastasija Cupic,Carles Martínez-Romero,Lubbertus C. F. Mulder,Thomas Kehrer,Soner Yildiz,Angela Choi,Ignacio Mena,Jana De Vrieze,Sadaf Aslam,Daniel Stadlbauer,David A. Meekins,Chester McDowell,Velmurugan Balaraman,Juergen A. Richt,Bruno G. De Geest,Lisa Miorin,Florian Krammer,Viviana Simon,Adolfo García-Sastre,Michael Schotsaert +21 more
TL;DR: In this paper, a mouse-adapted SARS-CoV-2 was serial passed through a clinical virus isolate in the lungs of mice and then used low doses of this virus in mouse models for advanced age, diabetes and obesity.
Journal ArticleDOI
Susceptibility of swine cells and domestic pigs to SARS-CoV-2
David A. Meekins,Igor Morozov,Jessie D. Trujillo,Natasha N. Gaudreault,Dashzeveg Bold,Mariano Carossino,Bianca Libanori Artiaga,Sabarish V. Indran,Taeyong Kwon,Velmurugan Balaraman,Daniel W. Madden,Heinz Feldmann,Jamie Henningson,Wenjun Ma,Wenjun Ma,Udeni B. R. Balasuriya,Juergen A. Richt +16 more
TL;DR: It is indicated that although different porcine cell lines are permissive to SARS-CoV-2, five-week old pigs are not susceptible to infection via oral/intranasal/intratracheal challenge and are not a suitable pre-clinical animal model to study Sars-Cov-2 pathogenesis or efficacy of respective vaccines or therapeutics.
Journal ArticleDOI
Infection and transmission of ancestral SARS-CoV-2 and its alpha variant in pregnant white-tailed deer.
Konner Cool,Natasha N. Gaudreault,Igor Morozov,Jessie D. Trujillo,David A. Meekins,Chester McDowell,Mariano Carossino,Dashzeveg Bold,Dana N Mitzel,Taeyong Kwon,Velmurugan Balaraman,Daniel W. Madden,Bianca Libanori Artiaga,Roman Pogranichniy,Gleyder Roman Sosa,Jamie Henningson,William C. Wilson,Udeni B. R. Balasuriya,Adolfo García-Sastre,Juergen A. Richt +19 more
TL;DR: In this paper, the authors investigated the susceptibility and transmission of SARS-CoV-2 in adult white-tailed deer (WTD) and found that adult WTD are highly susceptible to SARS infection and can transmit the virus through direct contact as well as vertically from doe to fetus.