D
David A. Parker
Researcher at Royal Dutch Shell
Publications - 43
Citations - 2152
David A. Parker is an academic researcher from Royal Dutch Shell. The author has contributed to research in topics: Bagasse & Cofactor. The author has an hindex of 22, co-authored 39 publications receiving 1814 citations. Previous affiliations of David A. Parker include Aberystwyth University & University of Exeter.
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Journal ArticleDOI
Metabolomic analysis reveals a common pattern of metabolic re-programming during invasion of three host plant species by Magnaporthe grisea.
David A. Parker,Manfred Beckmann,Hassan Zubair,David Enot,Zaira Caracuel-Rios,David P. Overy,Stuart Snowdon,Nicholas J. Talbot,John Draper +8 more
TL;DR: The results suggest that fungal pathogens deploy a common metabolic re-programming strategy in diverse host species to suppress plant defence and colonize plant tissue.
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Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli
Thomas P. Howard,Sabine Middelhaufe,Karen Moore,Christoph Edner,Dagmara M. Kolak,George N. Taylor,David A. Parker,David A. Parker,Rob Lee,Rob Lee,Nicholas Smirnoff,Stephen J. Aves,John Love +12 more
TL;DR: Production of petroleum-replica hydrocarbons in Escherichia coli is reported on to demonstrate the ability to design and implement artificial molecular pathways for the production of renewable, industrially relevant fuel molecules.
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New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition
Karl A. P. Payne,Mark D. White,Karl Fisher,Basile Khara,Samuel S. Bailey,David A. Parker,Nicholas J. W. Rattray,Drupad K. Trivedi,Royston Goodacre,Rebecca Beveridge,Perdita E. Barran,Stephen E. J. Rigby,Nigel S. Scrutton,Sam Hay,David Leys +14 more
TL;DR: It is shown that Fdc1 is solely responsible for the reversible decarboxylase activity, and that it requires a new type of cofactor: a prenylated flavin synthesized by the associated UbiX/Pad1, which offers new routes in alkene hydrocarbon production or aryl (de)carboxylation.
Journal ArticleDOI
Brachypodium distachyon: making hay with a wild grass
TL;DR: Brachypodium distachyon is a wild grass with a short life cycle and accessions collected from across its ancestral range show a surprising degree of phenotypic variation in many traits, including those implicated in domestication of the cereals.
Journal ArticleDOI
UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis
Mark D. White,Karl A. P. Payne,Karl Fisher,Stephen A. Marshall,David A. Parker,Nicholas J. W. Rattray,Drupad K. Trivedi,Royston Goodacre,Stephen E. J. Rigby,Nigel S. Scrutton,Sam Hay,David Leys +11 more
TL;DR: The mechanism for formation of a new flavin-derived cofactor required for the decarboxylase activity of UbiD is established, extending both flavin and terpenoid biochemical repertoires.