David A. Talmage

TL;DR: This Review attempts to identify areas of controversy, as well as consensus, on what is and is not yet known about how cholinergic signaling in the CNS contributes to normal cognitive processes, and delineates the findings from recent work on the extent to which Dysfunction of Cholinergic circuits contributes to cognitive decline associated with neurodegenerative disorders.

TL;DR: It is shown that the development of the thalamocortical projection, one of the most prominent tracts in the mammalian brain, depends on the early tangential migration of a population of neurons derived from the ventral telencephalon.

TL;DR: The data demonstrate the essential role of CRD-NRG-1-mediated signaling for coordinating nerve, target, and Schwann cell interactions in the normal maintenance of peripheral synapses, and ultimately in the survival ofCRD- NRG- 1-expressing neurons.

TL;DR: An overview of the literature at, or near, the interface of nicotinic receptors and appetite regulation is presented and the hypothesis that the lateral hypothalamus is a particularly important locus of the anorectic effects of nicotine is presented.

TL;DR: A family of ACh sensors based on G-protein-coupled receptors that has the sensitivity, specificity, signal-to-noise ratio, kinetics and photostability suitable for monitoring ACh signals in vitro and in vivo is developed.