D
David Gomez-Cabrero
Researcher at Universidad Pública de Navarra
Publications - 145
Citations - 7010
David Gomez-Cabrero is an academic researcher from Universidad Pública de Navarra. The author has contributed to research in topics: DNA methylation & Epigenetics. The author has an hindex of 30, co-authored 127 publications receiving 5351 citations. Previous affiliations of David Gomez-Cabrero include King Abdullah University of Science and Technology & Catalan Institution for Research and Advanced Studies.
Papers
More filters
Journal ArticleDOI
A survey of best practices for RNA-seq data analysis
Ana Conesa,Pedro Madrigal,Pedro Madrigal,Sonia Tarazona,David Gomez-Cabrero,Alejandra Cervera,Andrew McPherson,Michał Wojciech Szcześniak,Daniel J. Gaffney,Laura L. Elo,Xuegong Zhang,Ali Mortazavi +11 more
TL;DR: All of the major steps in RNA-seq data analysis are reviewed, including experimental design, quality control, read alignment, quantification of gene and transcript levels, visualization, differential gene expression, alternative splicing, functional analysis, gene fusion detection and eQTL mapping.
Journal ArticleDOI
A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data
Andrew E. Teschendorff,Francesco Marabita,Matthias Lechner,Thomas E. Bartlett,Jesper Tegnér,David Gomez-Cabrero,Stephan Beck +6 more
TL;DR: A novel model-based intra-array normalization strategy for 450 k data, called BMIQ (Beta MIxture Quantile dilation), to adjust the beta-values of type2 design probes into a statistical distribution characteristic of type1 probes is proposed.
Journal ArticleDOI
Data integration in the era of omics: current and future challenges.
David Gomez-Cabrero,Imad Abugessaisa,Dieter Maier,Andrew E. Teschendorff,Matthias Merkenschlager,Andreas Gisel,Esteban Ballestar,Erik Bongcam-Rudloff,Ana Conesa,Jesper Tegnér +9 more
TL;DR: A web-survey is used to assess current research projects on data-integration to tap into the views, needs and challenges as currently perceived by parts of the research community.
Journal ArticleDOI
An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform.
Francesco Marabita,Malin Almgren,Malene E. Lindholm,Sabrina Ruhrmann,Fredrik Fagerström-Billai,Maja Jagodic,Carl Johan Sundberg,Tomas J. Ekström,Andrew E. Teschendorff,Jesper Tegnér,David Gomez-Cabrero +10 more
TL;DR: A comparative analysis using a comprehensive data set suggests an efficient pipeline for proper identification of differentially methylated CpGs using the Illumina 450K arrays.
Journal ArticleDOI
An integrative analysis reveals coordinated reprogramming of the epigenome and the transcriptome in human skeletal muscle after training
Malene E. Lindholm,Francesco Marabita,David Gomez-Cabrero,Helene Rundqvist,Tomas J. Ekström,Jesper Tegnér,Carl Johan Sundberg +6 more
TL;DR: It is shown that highly consistent and associated modifications in methylation and expression, concordant with observed health-enhancing phenotypic adaptations, are induced by a physiological stimulus.