S
Sonia Tarazona
Researcher at Polytechnic University of Valencia
Publications - 55
Citations - 6094
Sonia Tarazona is an academic researcher from Polytechnic University of Valencia. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 17, co-authored 45 publications receiving 4749 citations. Previous affiliations of Sonia Tarazona include Polytechnic University of Puerto Rico & University of Valencia.
Papers
More filters
Journal ArticleDOI
A survey of best practices for RNA-seq data analysis
Ana Conesa,Pedro Madrigal,Pedro Madrigal,Sonia Tarazona,David Gomez-Cabrero,Alejandra Cervera,Andrew McPherson,Michał Wojciech Szcześniak,Daniel J. Gaffney,Laura L. Elo,Xuegong Zhang,Ali Mortazavi +11 more
TL;DR: All of the major steps in RNA-seq data analysis are reviewed, including experimental design, quality control, read alignment, quantification of gene and transcript levels, visualization, differential gene expression, alternative splicing, functional analysis, gene fusion detection and eQTL mapping.
Journal ArticleDOI
Differential expression in RNA-seq: A matter of depth
TL;DR: This work analyzed how sequencing depth affects the detection of transcripts and their identification as differentially expressed, and proposed a novel approach--NOISeq--that differs from existing methods in that it is data-adaptive and nonparametric.
Journal ArticleDOI
Qualimap: evaluating next generation sequencing alignment data
Fernando Garcia-Alcalde,Konstantin Okonechnikov,José Carbonell,Luis Miguel Cruz,Stefan Götz,Sonia Tarazona,Joaquín Dopazo,Thomas F. Meyer,Ana Conesa +8 more
TL;DR: Qualimap is a Java application that supports user-friendly quality control of mapping data, by considering sequence features and their genomic properties, and takes sequence alignment data and provides graphical and statistical analyses for the evaluation of data.
Journal ArticleDOI
Data quality aware analysis of differential expression in RNA-seq with NOISeq R/Bioc package
Sonia Tarazona,Pedro Furió-Tarí,David Turrà,Antonio Di Pietro,María José Nueda,Alberto Ferrer,Ana Conesa +6 more
TL;DR: It is demonstrated that the non-parametric NOISeqBIO efficiently controls false discoveries in experiments with biological replication and outperforms state-of-the-art methods.
Journal ArticleDOI
Next maSigPro: updating maSigPro bioconductor package for RNA-seq time series.
TL;DR: This work has updated maSigPro to support RNA-seq time series analysis by introducing generalized linear models in the algorithm to support the modeling of count data while maintaining the traditional functionalities of the package.