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David J. Lythgoe
Researcher at King's College London
Publications - 134
Citations - 4974
David J. Lythgoe is an academic researcher from King's College London. The author has contributed to research in topics: Psychosis & Glutamate receptor. The author has an hindex of 32, co-authored 108 publications receiving 3969 citations. Previous affiliations of David J. Lythgoe include University of London & South London and Maudsley NHS Foundation Trust.
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rBET: Making BET work for Rodent Brains
TL;DR: This modified rodent Brain Extraction Tool (rBET) is modified to use more appropriate initial estimates for the shape and location of the rodent brain, and also toUse more appropriate smoothness constraints.
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Resting state EEG power spectrum and functional connectivity in autism: a cross-sectional analysis
Pilar Garcés,Christopher H. Chatham,Stefan Holiga,Juergen Dukart,Emily J.H. Jones,Simon Baron-Cohen,S. Bölte,Jan K. Buitelaar,Sarah Durston,Bob Oranje,Antonio M. Persico,T. Bougeron,Flavio Dell'Acqua,Christine Ecker,Carolin Moessnang,Tony Charman,Julian Tillmann,Mark H. Johnson,Eva Loth,Daniel Brandeis,Jumana Ahmad,Sara Ambrosino,Bonnie Auyeung,Tobias Banaschewski,Sarah Baumeister,Christian F. Beckmann,Thomas Bourgeron,Carsten Bours,Michael Brammer,Claudia Brogna,Yvette G. E. de Bruijn,Bhismadev Chakrabarti,Ineke Cornelissen,Daisy Crawley,Guillaume Dumas,Jessica Faulkner,Vincent Frouin,David Goyard,Lindsay S. Ham,Hannah Hayward,Joerg F. Hipp,Rosemary Holt,Prantik Kundu,Meng-Chuan Lai,Xavier Liogier D’ ardhuy,Michael V. Lombardo,David J. Lythgoe,René C.W. Mandl,Andre F. Marquand,Luke Mason,Maarten Mennes,Andreas Meyer-Lindenberg,Nico Mueller,Declan G. Murphy,Beth Oakley,Laurence O'Dwyer,Marianne Oldehinkel,Gahan Pandina,Barbara Ruggeri,Amber N. V. Ruigrok,Jessica Sabet,Roberto Sacco,Antonia San José Cáceres,Emily Simonoff,Will Spooren,Roberto Toro,Heike Tost,Jack Waldman,Steven Williams,Caroline Wooldridge,Marcel P. Zwiers +70 more
TL;DR: In this article , the authors quantified resting state EEG alpha peak metrics, power spectrum (PS, 2-32 Hz) and functional connectivity (FC) in 411 children, adolescents and adults (n = 212 ASD, n = 199 neurotypicals [NT], all with IQ > 75).
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Adolescent-onset heavy cannabis use associated with significantly reduced glial but not neuronal markers and glutamate levels in the hippocampus.
Grace Blest-Hopley,Aisling O'Neill,Robin Wilson,Vincent Giampietro,David J. Lythgoe,Alice Egerton,Sagnik Bhattacharyya,Sagnik Bhattacharyya +7 more
TL;DR: Altered myoinositol levels may be a marker of glia dysfunction and is consistent with experimental preclinical evidence that cannabinoid‐induced glial dysfunction may underlie cannabinoid-induced memory impairments in CUs.
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The effects of callous-unemotional traits and aggression subtypes on amygdala activity in response to negative faces.
Pascal M Aggensteiner,Nathalie E. Holz,Boris William Böttinger,Sarah Baumeister,Sarah Hohmann,Julia E Werhahn,Jilly Naaijen,Shahrzad Ilbegi,Jeffrey C. Glennon,Pieter J. Hoekstra,Andrea Dietrich,Renee Kleine Deters,Melanie C Saam,Ulrike M E Schulze,David J. Lythgoe,Arjun Sethi,Michael C. Craig,Mathilde Mastroianni,Ilyas Sagar-Ouriaghli,Paramala Santosh,Mireia Rosa,Núria Bargalló,Josefina Castro-Fornieles,Celso Arango,Maria J Penzol,Jorge E. Vidal,Barbara Franke,Marcel P. Zwiers,Jan K. Buitelaar,Susanne Walitza,Tobias Banaschewski,Daniel Brandeis +31 more
TL;DR: The results showed differences in amygdala activity and SC responses to emotional faces between cases with ODD/CD and TD, while CU traits moderate both central (amygdala) and peripheral (SC) responses.
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Striatal structure and its association with N-Acetylaspartate and glutamate in autism spectrum disorder and obsessive compulsive disorder
Jilly Naaijen,Marcel P. Zwiers,Natalie J. Forde,Steven Williams,Sarah Durston,Daniel Brandeis,Jeffrey C. Glennon,Barbara Franke,David J. Lythgoe,Jan K. Buitelaar +9 more
TL;DR: Findings show involvement of NAA and glutamate in striatal volume in ASD and suggest greater asymmetry in paediatric ASD and OCD compared with controls, pointing to overlapping subcortical abnormalities.