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David J. Lythgoe
Researcher at King's College London
Publications - 134
Citations - 4974
David J. Lythgoe is an academic researcher from King's College London. The author has contributed to research in topics: Psychosis & Glutamate receptor. The author has an hindex of 32, co-authored 108 publications receiving 3969 citations. Previous affiliations of David J. Lythgoe include University of London & South London and Maudsley NHS Foundation Trust.
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The Development of Cognitive Control in Children with Autism Spectrum Disorders or Obsessive-Compulsive Disorder: A Longitudinal fMRI study
Bram Gooskens,Dienke J. Bos,Jilly Naaijen,Sophie E.A. Akkermans,Anna Kaiser,Sarah Hohmann,Muriel M K Bruchhage,Tobias Banaschewski,Daniel Brandeis,Steven Williams,David J. Lythgoe,Jan K. Buitelaar,Bob Oranje,Sarah Durston +13 more
TL;DR: The findings overall suggest that the development of cognitive control, as assessed by the stop signal task, is similar in children with and without ASD or OCD.
Journal ArticleDOI
Relationship between brain glutamate concentrations and functional outcome in individuals at ultra high risk of psychosis psychosis
Alice Egerton,James M. Stone,Christopher A. Chaddock,Gareth J. Barker,Ilaria Bonoldi,Kate Merritt,Paul Allen,David J. Lythgoe,Ruth L. O'Gorman,Philip McGuire +9 more
Journal ArticleDOI
Sensory salience processing moderates attenuated gazes on faces in autism spectrum disorder: a case–control study
Christine Ecker,Sarah Baumeister,Emily J.H. Jones,Declan G. Murphy,Gahan Pandina,Jumana Ahmad,Sara Ambrosino,Bonnie Auyeung,Tobias Banaschewski,Simon Baron-Cohen,Nico Bast,Christian F. Beckmann,S. Bölte,Thomas Bourgeron,Carsten Bours,Michael Brammer,Daniel Brandeis,Claudia Brogna,Yvette G. E. de Bruijn,Jan K. Buitelaar,Bhismadev Chakrabarti,Tony Charman,Ineke Cornelissen,Daisy Crawley,Flavio Dell'Acqua,Guillaume Dumas,Sarah Durston,Jessica Faulkner,Vincent Frouin,Pilar Garcés,David Goyard,Lindsay S. Ham,Hannah Hayward,Joerg F. Hipp,Rosemary Holt,Mark H. Johnson,Prantik Kundu,Meng-Chuan Lai,Xavier Liogier d'Ardhuy,Michael V. Lombardo,Eva Loth,David J. Lythgoe,René C.W. Mandl,Andre F. Marquand,Luke Mason,Maarten Mennes,Andreas Meyer-Lindenberg,Carolin Moessnang,Beth Oakley,Laurence O'Dwyer,Marianne Oldehinkel,Bob Oranje,Antonio M. Persico,Barbara Ruggeri,Amber N. V. Ruigrok,Jessica Sabet,Roberto Sacco,Antonia San José Cáceres,Emily Simonoff,Will Spooren,Julian Tillmann,Roberto Toro,Heike Tost,Jack Waldman,Steven Williams,Caroline Wooldridge,Marcel P. Zwiers,Christine M. Freitag +67 more
TL;DR: In this article , the locus coeruleus-norepinephrine system (LC-NE) has been established as a modulator of this sensory salience processing (SSP), and the hypothesis that altered LC-NE functioning contributes to different SSP and results in diverging social attention in ASD.
Journal ArticleDOI
Sailing in rough waters: Examining volatility of fMRI noise
TL;DR: In this article, the Hurst parameter H ∈ ǫ(0, 1) was used to model the volatility of the realised volatility of fMRI noise, which is not only non-constant but also substantially more irregular than a standard Brownian motion.
Posted ContentDOI
Hippocampal Glutamate, Resting Perfusion and the Effects of Cannabidiol in Psychosis Risk
Cathy Davies,Matthijs G. Bossong,Daniel Martins,R. Wilson,Elizabeth Appiah-Kusi,Grace Blest-Hopley,Paul D. Allen,Fernando Zelaya,David J. Lythgoe,Micheal J. Brammer,Jessica M. Perez,Philip McGuire,Sagnik Bhattacharyya +12 more
TL;DR: In this article , a double-blind, parallel-group design was used to measure glutamate concentrations in left hippocampus in patients at Clinical High Risk (CHR) for psychosis, and a significant linear relationship was observed across groups, such that glutamate was highest in controls, lowest in CHR-placebo and intermediate in patients under CBD (p=.031).