D
David M. Jacobowitz
Researcher at National Institutes of Health
Publications - 389
Citations - 26961
David M. Jacobowitz is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Calretinin & Hypothalamus. The author has an hindex of 84, co-authored 389 publications receiving 26673 citations. Previous affiliations of David M. Jacobowitz include Uniformed Services University of the Health Sciences & Hebrew University of Jerusalem.
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A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
TL;DR: The N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey provides a model that can be used to examine mechanisms and explore therapies of parkinsonism and the pathological and biochemical changes produced by NMPTP are similar to the well-established changes in patients with parkinsonistan.
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Topographic atlas of catecholamine and acetylcholinesterase-containing neurons in the rat brain. I. Forebrain (telencephalon, diencephalon).
TL;DR: A detailed stereotaxic atlas of the catecholaminergic and acetylcholinesterase‐containing neural structures is presented.
Journal Article
Pharmacological Actions of 6-Hydroxydopamine
TL;DR: Time-course studies have determined the threshold for terminal destruction in various organs of several species and the increasing order of the destructive action of 6-OHDA in various end organs is cardiac ventricles, salivary glands, and blood vessels.
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Immunohistochemical mapping of galanin-like neurons in the rat central nervous system
TL;DR: The localization of the GA-like immunoreactivity in the locus coeruleus suggests a partial coexistence with catecholaminergic neurons as well as a possible involvement of theGA-like peptide in a neuroregulatory role.
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Local circuit neurons immunoreactive for calretinin, calbindin D-28k or parvalbumin in monkey prefrontal cortex: distribution and morphology.
Françoise Condé,Jennifer S. Lund,David M. Jacobowitz,Kenneth G. Baimbridge,A M D David Lewis +4 more
TL;DR: This study used immunohistochemical techniques to characterize and compare the morphological features and distribution in macaque monkey prefrontal cortex of local circuit neurons that contain each of the calretinin, calbindin, and parvalbumin proteins.